Results 221 to 230 of about 4,980,484 (299)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

The Influence of Psychological Stress and Stress-Related Disorders in the Treatment Outcome of Periodontitis: A Systematic Review and Meta-Analysis. [PDF]

J Clin Periodontol
Mauland EK, Neupane SP.
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Treatment Preferences in Patients With Insomnia and Medical Comorbidity: Associated Factors and Impact on Treatment-Outcome. [PDF]

J Sleep Res
Rauwerda N, Pot I, Braamse A, van Straten A, van Nieuwkerk P, Boss M, Rikkert M, Knoop H.   +7 more
europepmc   +1 more source

Evidence for a relationship between concentrations of nucleos/tide analogue agents and treatment outcome in chronic hepatitis B infection: A systematic review

Sukali G, Anderson M, Mohammed KS, Biggs P, Delphin M, Redmond JM, Maponga T, Govender K, Amponsah SK, Alffenaar J, Waitt C, Iwuji C, Matthews PC.   +12 more
europepmc   +1 more source

NEAT1 lncRNA overexpression results in short-term progression and poor treatment outcome in childhood B-ALL. [PDF]

Br J Haematol
Xagorari M, Marmarinos A, Doganis D, Nikita M, Magkou E, Sfetsiori AE, Baka M, Kossiva L, Pasparaki S, Soldatou A, Tsolia M, Scorilas A, Gourgiotis D, Avgeris M.   +13 more
europepmc   +1 more source

Treatment outcome and associated factors of acute heart failure in East Africa, an Ethiopian perspective: A systematic review and meta-analysis. [PDF]

Am Heart J Plus
Belayneh AG, Andargie GA, Seid K, Lakew G, Yirsaw AN, Tefera M, Bogale EK, Anagaw TF, Fenta ET, Endeshaw D, Adal O, Tareke AA, Kebede N, Jemberu L, Getachew E.   +14 more
europepmc   +1 more source