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Treatment-Resistant Schizophrenia
Psychiatric Clinics of North America, 2007This article opens with a brief history of pharmacologic treatment of schizophrenia. It then discusses the definition and treatment of treatment-resistant schizophrenia, with particular attention to clinical, biological and neuroimaging correlates, as well as the best treatment options, including the use of clozapine in patients who meet the definition
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Resistant hypertension: resistance to treatment or resistance to taking treatment?
Heart, 2014The treatment of hypertension has been a therapeutic success. A generation or more of effective drugs deserves considerable credit for their contribution to the substantial decline in age-related incidence of stroke, ischaemic heart disease and heart failure. And because almost all the drugs are long-since off patent, the cost of success comes cheaply.
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Targeting Treatment-Resistant Depression
Journal of Pharmacy Practice, 2011Only 50% of depressed patients achieve remission of symptoms after 2 trials of antidepressants. Therefore one half of patients are considered treatment resistant. Studies have shown that with each failed antidepressant, chances of remission continue to decline. Untreated depressive symptoms lead to impaired social and occupational function, decline of
Monica, Mathys, Brian G, Mitchell
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Treatment-resistant inflammatory myopathy
Best Practice & Research Clinical Rheumatology, 2010When confronted with a dermatomyositis or polymyositis patient not responding to immunosuppressive treatment, physicians must first ask whether the original diagnosis was correct. In this review, we provide a guide to the clinical features and ancillary tests, which might be helpful in the differential diagnosis of myositis.
Herman F, Mann +2 more
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TREATMENT OF “RESISTANT” FIBROMYALGIA
Rheumatic Disease Clinics of North America, 1995Long-term outcome for the majority of patients with fibromyalgia is sufficiently disappointing so that most patients can be considered to have "resistant" disease. Among published treatments, education, active exercise, and nighttime antidepressant medications perform best. Patients eligible for treatment include those with primarily regional symptoms,
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Treatment of Resistant Hypertension
2018Hypertension cannot always be controlled by the classical antihypertensive treatment strategies whose therapeutic failure leads to a condition known as resistant hypertension [1]. This chapter will discuss the prevalence within a hypertensive state of individuals in whom blood pressure (BP) remains uncontrolled despite appropriate treatment.
Seravalle, G, Grassi, G, Mancia, G
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Defining treatment‐resistant depression
Depression and Anxiety, 2019Varying conceptualizations of treatment-resistant depression (TRD) have made translating research findings or systematic reviews into clinical practice guidelines challenging and inconsistent.We conducted a review for the Centers for Medicare & Medicaid Services and the Agency for Healthcare Research and Quality to clarify how experts and investigators
Bradley N. Gaynes +12 more
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Managing Treatment-Resistant Patients
High Blood Pressure & Cardiovascular Prevention, 2015Treatment-resistant hypertension (TRH) has a prevalence of approximately 10-20 %, and up to 5 % of patients with TRH experience a major cardiovascular or cerebrovascular event each year. Effective management of real TRH is important but can present a significant clinical challenge.
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Treatment-Resistant Panic Disorder
CNS Spectrums, 2004AbstractA substantial number of patients with panic disorder and agoraphobia may remain symptomatic after standard treatment (including selective serotonin reuptake inhibitors, tricyclic antidepressants, benzodiazepines, or irreversible monamine oxidase inhibitors).
Borwin, Bandelow, Eckart, Rüther
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Treatment of resistant hypertension
Current Hypertension Reports, 2005Although the true prevalence of resistant hypertension is not known, it is likely that this condition will become increasingly common, driven by an aging population, obesity, nonadherence trends, and effects of target-organ disease. Current approaches focus on two goals: evaluation and correction of contributing causes, then selection of an effective ...
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