Results 61 to 70 of about 2,255,193 (285)

Risk factors for drug resistant tuberculosis in Leicestershire - poor adherence to treatment remains an important cause of resistance [PDF]

, 2013
In the light of rising numbers of tuberculosis (TB) cases in the United Kingdom, the problem of anti-tubercular drug resistance remains a significant concern.
Hayward, AC, Monk, PN, Neal, KR, Pritchard, AJ   +3 more
core   +2 more sources

Treatment Resistant Hypertension

Ethnicity & Disease, 2015
<p>Treatment resistant hypertension (TRH) is defined by office blood pressure (BP) uncontrolled on ≥3 or controlled on ≥4 antihypertensive medications, preferably at optimal doses and including a diuretic. Apparent (a)TRH is used when optimal therapy, adherence, and measurement artifacts are unknown.
openaire   +3 more sources

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Psychological Treatments for People With Severe and Enduring Anorexia Nervosa: A Mini Review

Frontiers in Psychiatry, 2020
This Mini-Review presents recent research into evidence for psychological treatments for people with severe and enduring anorexia nervosa (SEAN). Two psychological therapies, specialist supportive clinical management (SSCM), and cognitive behavior ...
James Zhu, Yive Yang, Stephen Touyz, Stephen Touyz, Rebecca Park, Phillipa Hay, Phillipa Hay   +6 more
doaj   +1 more source

Cognition in Treatment Resistant versus Non- Treatment Resistant Schizophrenia [PDF]

Eur Psychiatry
IntroductionDespite antipsychotic treatment, around one-third of individuals of schizophrenia remain unresponsive.ObjectivesComparing cognitive impairments in TRS versus non-TRS patients.Methods50 adult patients with schizophrenia(DSM-5) were recruited in this cross-sectional cohort study, categorised into TRS (14) (treatment-resistant schizophrenia ...
Shah S, Patel K, Bhandari A, Porwal A, Lalwani N.   +4 more
europepmc   +3 more sources

Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients. [PDF]

, 2012
Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration of drugs used ...
Alfredo Ponce-de-Leon, Andrea Benedetti, Carlos Pérez-Guzmán, Carlton Evans, Carole D. Mitnick, Chen-Yuan Chiang, Chi Chiu Leung, Christophe Lange, David Ashkin, Dennis Falzon, Dick Menzies, Domingo Palmero, Donald Enarson, Eward D. Chan, Geoffrey Pasvol, Giovanni B. Migliori, Giovanni Sotgiu, H. Simon Schaaf, Helen Cox, Hye-Ryoun Kim, Jae-Joon Yim, Jamie N. Bayona, Janice Westenhouse, Jennifer Flood, Jerome Robert, Jiehui Li, Joey Lancaster, Jose Peña, José Sifuentes-Osornio, Katherine Flanagan, Kathy DeRiemer, Kwonjune J. Seung, Leah G. Jarlsberg, Lena Shah, Lia D'Ambrosio, Madhukar Pai, Marcos Burgos, Maria G. Hollm-Delgado, Maria I. D. Quelapio, Maria L. Garcia-Garcia, Mario H. Vargas, Martie Van der Walt, Masa Narita, Matthew J. Strand, Melissa Bauer, Mercedes C. Becerra, Michael D. Iseman, Monika Avendano, Neel Gandhi, Nguyen Huy Dung, Payam Tabarsi, Philly O'Riordan, Pirett Viiklepp, Reuben M. Granich, Rita Banerjee, Robert van Altena, Rosella Centis, Salmaan Keshavjee, Sarah Royce, Sergey P. Mishustin, Seung-kyu Park, Shama D. Ahuja, Sonya S. Shin, Tae Sun Shim, Thelma E. Tupasi, Timothy H. Holtz, Tjip S. Van der Werf, Vaira Leimane, Vija Riekstina, Wiel C. M. de Lange, Wing Wai Yew, Won-Jung Koh, Yuji Shiraishi   +72 more
core   +9 more sources

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells. [PDF]

, 2017
Metformin is a widely used agent for the treatment of diabetes and infertility, however, it has been found to have anti-cancer effects in a variety of malignancies including high grade serous ovarian cancer (HGSC).
Aspuria, Paul-Joseph P, Hodeib, Melissa, Karlan, Beth Y, Lunt, Sophia Y, Ogrodzinski, Martin P, Reue, Karen, Vergnes, Laurent   +6 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source