The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Long-term survival after surgical treatment for post-infarction mechanical complications: results from the Caution study [PDF]
Matteo Matteucci +32 more
openalex +1 more source
Treatment patterns and clinical outcomes in 157 patients with extensive-stage small cell lung cancer: real-world evidence from a single-center retrospective study [PDF]
, 2023 Yumin Zheng +6 more
openalex +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Feasibility of wearable activity tracking devices to measure physical activity and sleep change among adolescents with chronic pain-a pilot nonrandomized treatment study. [PDF]
Front Pain Res (Lausanne), 2023 Junghans-Rutelonis A +5 more
europepmc +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Quantitative ASL Perfusion and Vessel Wall MRI in Tuberculous Meningitis: A Pre- and Post-Treatment Study. [PDF]
J Clin MedWang Y, Xu Z, Xu D, Hou D.
europepmc +1 more source
Clinicopathological analysis and prognostic treatment study of angiosarcoma of the breast: a SEER population-based analysis. [PDF]
World J Surg Oncol, 2023 Teng L +5 more
europepmc +1 more source
Study and development of acoustic treatment for jet engine tailpipes [PDF]
A study and development program was accomplished to attenuate turbine noise generated in the JT3D turbofan engine. Analytical studies were used to design an acoustic liner for the tailpipe.
Dinwiddie, B. A., III +3 more
core +1 more source