Establishing Simultaneous T Cell Receptor Excision Circles (TREC) and K-Deleting Recombination Excision Circles (KREC) Quantification Assays and Laboratory Reference Intervals in Healthy Individuals of Different Age Groups in Hong Kong [PDF]
The clinical experience gathered throughout the years has raised awareness of primary immunodeficiency diseases (PIDD). T cell receptor excision circles (TREC) and kappa-deleting recombination excision circles (KREC) assays for thymic and bone marrow ...
Janette S Y Kwok, Patrick Ip
exaly +4 more sources
Regional and gender disparities in tobacco-related esophageal cancer: Insights from the Global Burden of Disease study 1990–2021 [PDF]
Introduction Tobacco-related esophageal cancer (TREC) is a major public health concern, with incidence and mortality rates rising globally. This study aims to analyze worldwide epidemiological data on TREC, examining its disease burden and temporal ...
Jinlong Chen+ +10 more
doaj +2 more sources
TREC and KREC Levels as a Predictors of Lymphocyte Subpopulations Measured by Flow Cytometry [PDF]
Primary immunodeficiency diseases (PID) is a heterogeneous group of disorders caused by genetic defects of the immune system, which manifests clinically as recurrent infections, autoimmune diseases, or malignancies. Early detection of other PID remains a
Ilya Korsunskiy +27 more
doaj +2 more sources
Primer estudio piloto para el tamizaje neonatal de linfopenias T y B en Colombia [PDF]
Introducción. La detección temprana de linfopenias congénitas facilitaría su tratamiento oportuno y la prevención de complicaciones serias, y optimizaría los recursos del sistema de salud. Objetivo. Realizar un estudio piloto para el tamizaje neonatal de
Sebastián Gutiérrez-Hincapié +4 more
doaj +2 more sources
Background: T and B cell-mediated immunity can be assessed using T cell receptor excision circle (TREC) and Kappa-deleting recombination excision circle (KREC) analysis, respectively, and successful implementation of this method requires evaluation of ...
Andrey A Savchenko +2 more
exaly +3 more sources
Validation on the First-Tier Fully Automated High-Throughput <i>SMN1</i>, <i>SMN2</i>, TREC, and <i>RPP30</i> Quantification by Quadruplex Droplet Digital PCR for Newborn Screening for Spinal Muscular Atrophy and Severe Combined Immunodeficiency. [PDF]
Mak CM +9 more
europepmc +2 more sources
Design and Validation of a Low-Level Controller for Hierarchically Controlled Exoskeletons
In this work, a generalized low-level controller is presented for sensor collection, motor input, and networking with a high-level controller. In hierarchically controlled exoskeletal systems, which utilize series elastic actuators (SEAs), the hardware ...
Connor W. Herron +5 more
doaj +1 more source
Implementation of TREC/KREC detection protocol for newborn SCID screening in Bulgaria: a pilot study
Neonatal screening for inborn errors of immunity (IEI), based on quantification of T-cell-receptor- excision circles (TRECs) and kappa-deleting recombination-excision circles (KRECs) from dried blood spots (DBS), allows early diagnosis and improved ...
Marina Marinova +6 more
doaj +1 more source
The TREC/KREC assay for the diagnosis and monitoring of patients with DiGeorge syndrome. [PDF]
DiGeorge syndrome (DGS) presents with a wide spectrum of thymic pathologies. Nationwide neonatal screening programs of lymphocyte production using T-cell recombination excision circles (TREC) have repeatedly identified patients with DGS.
Eva Froňková +13 more
doaj +1 more source
Screening diagnosis of primary immunodeficiencies in the practice of an allergist-immunologist
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L. Y. Barycheva +3 more
doaj +1 more source

