Results 31 to 40 of about 1,675,375 (319)

Deep Tree Net-Vector of Locally Aggregated Descriptor (VLAD) Model

open access: yesIEEE Access, 2019
In this work, we combined both a tree and a NetVLAD (vector of locally aggregated descriptors) in order to design new deep model. In developing this model, we studied the impact of tree hyperparameters and found that branch factors had major effects on ...
Abduljawad A. Amory   +2 more
doaj   +1 more source

Taxonium, a web-based tool for exploring large phylogenetic trees

open access: yeseLife, 2022
The COVID-19 pandemic has resulted in a step change in the scale of sequencing data, with more genomes of SARS-CoV-2 having been sequenced than any other organism on earth.
Theo Sanderson
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Rowan Tree Church Annual Report, 1993 [PDF]

open access: yes, 1993
This digital asset was created from the original digital scans by Rev. Paul V. Beyerl and provided to the Valdosta State University, Archives & Special Collections to be part of their Rowan Tree Church Periodicals Collection of the New Age Movements ...
Rowan Tree Church
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

The Rowan Tree Church 1995-1996 Annual Report [PDF]

open access: yes, 1995
This digital asset was created from the original digital scans by Rev. Paul V. Beyerl and provided to the Valdosta State University, Archives & Special Collections to be part of their Rowan Tree Church Periodicals Collection of the New Age Movements ...
Rowan Tree Church
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The Rowan Tree Church Annual Report for 1993-1994 [PDF]

open access: yes, 1994
This digital asset was created from the original digital scans by Rev. Paul V. Beyerl and provided to the Valdosta State University, Archives & Special Collections to be part of their Rowan Tree Church Periodicals Collection of the New Age Movements ...
Rowan Tree Church
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

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