Results 41 to 50 of about 1,224,461 (319)

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

The limiting equation for Neumann Laplacians on shrinking domains

open access: yesElectronic Journal of Differential Equations, 2000
Let ${Omega_{epsilon} }_{0 < epsilon le1}$ be an indexed family of connected open sets in ${mathbb R}^2$, that shrinks to a tree $Gamma$ as $epsilon$ approaches zero. Let $H_{Omega_{epsilon}}$ be the Neumann Laplacian and $f_{epsilon}$ be the restriction
Yoshimi Saito
doaj  

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Choosing the exponent in the definition of the connectivity index [PDF]

open access: yesJournal of the Serbian Chemical Society, 2001
Let du denote the degree of the vertex u of a molecular graph G. Then the connectivity index of G is defined as C (l) = G (l; C) = S (dudu)l, where the summation goes over all pairs of adjacent vertices. The exponent l is usually chosen to be equal to –1/
MIRKO LEPOVIC, IVAN GUTMAN
doaj  

Protecting trees through an inventory and typology: Heritage trees in the Karavanke Mountains, Slovenia

open access: yesActa Geographica Slovenica, 2011
Both research and policy require a transparent approach to monitoring and managing natural and cultural heritage because landscape quality has become a key concept in landscape planning.
Mateja Šmid Hribar, Anka Lisec
doaj   +1 more source

On the Aα-Spectral Radii of Cactus Graphs

open access: yesMathematics, 2020
Let A ( G ) be the adjacent matrix and D ( G ) the diagonal matrix of the degrees of a graph G, respectively. For 0 ≤ α ≤ 1 , the A α -matrix is the general adjacency and signless Laplacian spectral matrix having the form of
Chunxiang Wang   +3 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

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