Results 51 to 60 of about 1,487,086 (297)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Crown structure indicates tree secondary growth, competition legacy, and growth potential of dominant species in Europe

Ecological Indicators
Crown trait-based ecology has significantly advanced, yet a substantial knowledge gap remains regarding its predictive power on internal tree morphology and future growth potential across different species.
Shamim Ahmed, Torben Hilmers, Enno Uhl, Frederico Tupinambá-Simões, Felipe Bravo, Miren del Río, Hans Pretzsch   +6 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Groundcover improves nutrition and growth of citrus trees and reduces water runoff, soil erosion and nutrient loss on sloping farmland

Frontiers in Plant Science
IntroductionGroundcover management plays a crucial role in improving water retention and soil nutrition in orchard systems, thereby preventing environmental constrains by non-point source pollution.
Rui Liu, Rui Liu, Yuting Zhang, Yuting Zhang, Zhichao Wang, Xueliang Zhang, Wenjing Xu, Jianwei Zhang, Yueqiang Zhang, Yueqiang Zhang, Bin Hu, Xiaojun Shi, Xiaojun Shi, Heinz Rennenberg   +13 more
doaj   +1 more source

Some important growing characteristics of apple and apricot cultivars in two fruit growing regions in Romania

International Journal of Horticultural Science, 2005
The aim of this study was to determine some important growing characteristics of 5 resistant apple (Rajka, Rubinola, Topaz, Otawa and Goldstar) and 7 apricot (NJA 19, Goldrich, Harcot, Venus, Comando, Olimp, Cea mai buna de Ungaria) cultivars in two ...
S. Pantea
doaj   +1 more source

Performance and Genetic Parameters of Poplar Hybrids and Clones in a Field Trial Are Modified by Contrasting Environmental Conditions during the Vegetative Propagation Phase

Plants, 2022
This study investigates epigenetics-like phenomena: how performance phenotypic plasticity, genotypic variation, and the heritability of growth traits and total phenolic compounds of Populus hybrids and clones in field trials may be modified by ...
Valda Gudynaitė-Franckevičienė, Alfas Pliūra   +1 more
doaj   +1 more source

Assessment of the role of age and light availability in leaf mortality in mango tree.[OS 6-1] [PDF]

, 2018
The branch autonomy principle states that the branch carbohydrate economy can be largely independent of the other branches of a tree. This may influence fruit growth and affect global crop yield.
Boudon, Frédéric, Fournier, Christian, Grechi, Isabelle, Lechaudel, Mathieu, Marquier, André, Normand, Frédéric, Soria, Christian   +6 more
core  

Lianas Suppress Seedling Growth and Survival of 14 Tree Species in a Panamanian Tropical Forest [PDF]

, 2016
Lianas are a common plant growth form in tropical forests, where they compete intensely with trees, decreasing tree recruitment, growth, and survival. If the detrimental effects of lianas vary significantly with tree species identity, as is often assumed,
Andrade, Beer, Bonan, Cahill, Cai, Carsten, Cavelier, Celis, Chen, Chen, Chittibabu, Clark, Clark, Cordero, Croat, Gibbs, Heijden, Heijden, Heijden, Hooper, IBM SPSS, Ingwell, Jennifer S. Powers, Kainer, Kira, Kitajima, Kitajima, Kurzel, Laura Martínez-Izquierdo, Laurance, Leigh, Lewis, María M. García, Nichols, Pan, Peña-Claros, Phillips, Poorter, Putz, Pérez-Salicrup, Pérez-Salicrup, Schnitzer, Schnitzer, Schnitzer, Schnitzer, Schnitzer, Schnitzer, Schnitzer, Schnitzer, Schnitzer, Schnitzer, Stefan A. Schnitzer, Stevens, Tanner, Tobin, Toledo-Aceves, Toledo-Aceves, Vleut, Windsor, Wright, Wright, Wright, Wyka, Yavitt, Zahawi, Álvarez-Cansino   +65 more
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Regional variation in growth and survival responses to atmospheric nitrogen and sulfur deposition for 140 tree species across the United States

Frontiers in Forests and Global Change
Atmospheric deposition of nitrogen (N) and sulfur (S) alter tree demographic processes via changes in nutrient pools, soil acidification, and biotic interactions.
Rebecca M. Dalton, Jesse N. Miller, Tara Greaver, Robert D. Sabo, Kemen G. Austin, Jennifer N. Phelan, R. Quinn Thomas, R. Quinn Thomas, Christopher M. Clark   +8 more
doaj   +1 more source