Results 31 to 40 of about 76,915 (267)

Experimental reconstruction of monsoon drought variability for Australasia using tree rings and corals

Geophysical Research Letters, 2008
An experimental reconstruction uses three well‐dated, annually‐resolved proxies from Australasia (0–40°S, 95–155°E) to provide large‐scale information on Sep–Jan Australasian monsoon variability based on the Palmer Drought Severity Index (PDSI) for 1787 ...
Rosanne D'Arrigo, Patrick Baker, Jonathan Palmer, Kevin Anchukaitis, Garry Cook   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Drought intensity affects radial growth and recovery of P. schrenkiana at varying elevations in the Western Tianshan Mountains, China

Forest Ecosystems
As climate change intensifies, forests increasingly face the challenges posed by more frequent and severe droughts. However, the impacts of drought intensity on post-drought growth recovery and compensatory growth in trees remain poorly understood ...
Qiaoling Yang, Guili Sun, Guangyu Wang, Kexiang Liu, Zhinian Yang, Li Qin, Arman Abula, Fan Xie, Ruibo Zhang   +8 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

A Framework for Determining Population-Level Vulnerability to Climate: Evidence for Growth Hysteresis in Chamaecyparis thyoides Along Its Contiguous Latitudinal Distribution

Frontiers in Forests and Global Change, 2020
The impact of ecological and climatological factors on individual organisms over time and space is inherently complex and creates substantial uncertainty about how climate change will influence the global biosphere. To understand some of this complexity,
Neil Pederson, Caroline Leland, Daniel A. Bishop, Daniel A. Bishop, Jessie K. Pearl, Jessie K. Pearl, Kevin J. Anchukaitis, Tessa Mandra, Myvonwynn Hopton-Ahmed, Dario Martin-Benito   +9 more
doaj   +1 more source

Tropical volcanoes synchronize eastern Canada with Northern Hemisphere millennial temperature variability

Nature Communications, 2022
A maximum latewood density based summer temperature reconstruction from eastern Canada shows recent warming is unprecedented over 1246 years, and tropical volcanism synchronizes regional and hemispheric summer temperatures at the multidecadal time scale.
Feng Wang, Dominique Arseneault, Étienne Boucher, Fabio Gennaretti, Shulong Yu, Tongwen Zhang   +5 more
doaj   +1 more source

Chemical Composition Characteristics and Source Contributions of Precipitation in Typical Cities on the North Slope of Tianshan Mountain in Xinjiang during 2010–2019

Atmosphere, 2022
This work presents the results of a ten-year investigation (2010–2019) on the characteristics and sources of precipitation pollution in typical cities locating in the economic belt on the North Slope of Tianshan Mountain, Xinjiang. The water-soluble ions’
Yuting Zhong, Xia Li, Ziang Fan, Maulen Ayitken, Shuting Li, Xinchun Liu   +5 more
doaj   +1 more source

The Ringing of Trees [PDF]

Bulletin of Miscellaneous Information (Royal Gardens, Kew), 1914
n ...
openaire   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source