Results 41 to 50 of about 73,689 (266)

Tracing ancient solar cycles with tree rings and radiocarbon in the first millennium BCE

open access: yesNature Communications
The Sun drives Earth’s energy systems, influencing weather, ocean currents, and agricultural productivity. Understanding solar variability is critical, but direct observations are limited to 400 years of sunspot records.
Nicolas Brehm   +7 more
doaj   +1 more source

Publisher Correction: Rapid 14C excursion at 3372-3371 BCE not observed at two different locations

open access: yesNature Communications, 2021
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21647 ...
A. J. Timothy Jull   +9 more
doaj   +1 more source

Apportionment of Chemical Components and Sources of PM2.5 in Shihezi City of Xinjiang, China

open access: yesAtmosphere, 2023
In order to reveal the pollution characteristics and sources of PM2.5, in this study, we collected PM2.5 filter membrane samples in Shihezi continuously from December 2020 to January 2021, and analyzed 10 kinds of water-soluble inorganic ions (WSIIs) and
Yuting Zhong   +5 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Wave of fire: an anthropogenic signal in historical fire regimes across central Pennsylvania, USA

open access: yesEcosphere, 2018
Increasingly detailed records of long‐term fire regime characteristics are needed to test ecological concepts and inform natural resource management and policymaking. We reconstructed and analyzed twelve 350+ yr‐long fire scar records developed from 2612
Michael C. Stambaugh   +6 more
doaj   +1 more source

High temperatures constrain latewood formation in Larix gmelinii xylem in boreal forests

open access: yesGlobal Ecology and Conservation, 2021
In trees, both radial growth and earlywood or latewood differentiation of xylem can reflect responses not only to internal stimuli but also to changes in the external environment.
Yuting Jin   +5 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Placing 21st Century Warming in Southern California, USA in a Multi-Century Historical Context

open access: yesAtmosphere
Warming in southern California during the 21st century is unprecedented in the instrumental record. To place this warming in a multi-century historical context, we analyzed tree ring data sampled from Jeffrey pine (Pinus jeffreyi) and sugar pine (Pinus ...
Paul A. Knapp   +2 more
doaj   +1 more source

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