Results 41 to 50 of about 73,829 (266)

Tracing ancient solar cycles with tree rings and radiocarbon in the first millennium BCE

Nature Communications
The Sun drives Earth’s energy systems, influencing weather, ocean currents, and agricultural productivity. Understanding solar variability is critical, but direct observations are limited to 400 years of sunspot records.
Nicolas Brehm, Charlotte L. Pearson, Marcus Christl, Alex Bayliss, Kurt Nicolussi, Thomas Pichler, David Brown, Lukas Wacker   +7 more
doaj   +1 more source

Publisher Correction: Rapid 14C excursion at 3372-3371 BCE not observed at two different locations

Nature Communications, 2021
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21647 ...
A. J. Timothy Jull, Irina P. Panyushkina, Mihály Molnár, Tamás Varga, Lukas Wacker, Nicolas Brehm, Elemér Laszló, Chris Baisan, Matthew W. Salzer, Willy Tegel   +9 more
doaj   +1 more source

Apportionment of Chemical Components and Sources of PM_2.5 in Shihezi City of Xinjiang, China

Atmosphere, 2023
In order to reveal the pollution characteristics and sources of PM2.5, in this study, we collected PM2.5 filter membrane samples in Shihezi continuously from December 2020 to January 2021, and analyzed 10 kinds of water-soluble inorganic ions (WSIIs) and
Yuting Zhong, Youjiang He, Xia Li, Shuting Li, Maulen Ayitken, Xinchun Liu   +5 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Wave of fire: an anthropogenic signal in historical fire regimes across central Pennsylvania, USA

Ecosphere, 2018
Increasingly detailed records of long‐term fire regime characteristics are needed to test ecological concepts and inform natural resource management and policymaking. We reconstructed and analyzed twelve 350+ yr‐long fire scar records developed from 2612
Michael C. Stambaugh, Joseph M. Marschall, Erin R. Abadir, Benjamin C. Jones, Patrick H. Brose, Daniel C. Dey, Richard P. Guyette   +6 more
doaj   +1 more source

High temperatures constrain latewood formation in Larix gmelinii xylem in boreal forests

Global Ecology and Conservation, 2021
In trees, both radial growth and earlywood or latewood differentiation of xylem can reflect responses not only to internal stimuli but also to changes in the external environment.
Yuting Jin, Junxia Li, Xueping Bai, Ying Zhao, Di Cui, Zhenju Chen   +5 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Placing 21st Century Warming in Southern California, USA in a Multi-Century Historical Context

Atmosphere
Warming in southern California during the 21st century is unprecedented in the instrumental record. To place this warming in a multi-century historical context, we analyzed tree ring data sampled from Jeffrey pine (Pinus jeffreyi) and sugar pine (Pinus ...
Paul A. Knapp, Avery A. Catherwood, Peter T. Soulé   +2 more
doaj   +1 more source