Results 51 to 60 of about 628,378 (346)
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Publisher Correction: Rapid 14C excursion at 3372-3371 BCE not observed at two different locations
Nature Communications, 2021 A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21647 ...
A. J. Timothy Jull +9 more
doaj +1 more source
Slow carbon and nutrient accumulation in trees established following fire exclusion in the southwestern United States. [PDF]
, 2016 Increasing tree density that followed fire exclusion after the 1880s in the southwestern United States may have also altered nutrient cycles and led to a carbon (C) sink that constitutes a significant component of the U.S. C budget.
Covington, W Wallace +4 more
core +2 more sources
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Tracing ancient solar cycles with tree rings and radiocarbon in the first millennium BCE
Nature CommunicationsThe Sun drives Earth’s energy systems, influencing weather, ocean currents, and agricultural productivity. Understanding solar variability is critical, but direct observations are limited to 400 years of sunspot records.
Nicolas Brehm +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman +9 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source
Wave of fire: an anthropogenic signal in historical fire regimes across central Pennsylvania, USA
Ecosphere, 2018 Increasingly detailed records of long‐term fire regime characteristics are needed to test ecological concepts and inform natural resource management and policymaking. We reconstructed and analyzed twelve 350+ yr‐long fire scar records developed from 2612
Michael C. Stambaugh +6 more
doaj +1 more source
High temperatures constrain latewood formation in Larix gmelinii xylem in boreal forests
Global Ecology and Conservation, 2021 In trees, both radial growth and earlywood or latewood differentiation of xylem can reflect responses not only to internal stimuli but also to changes in the external environment.
Yuting Jin +5 more
doaj +1 more source
, 2017 Tropical tree rings have the potential to yield valuable ecological and climate information, on the condition that rings are annual and accurately dated.
Baker, JCA +3 more
core +1 more source