Results 41 to 50 of about 623,719 (338)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Frontiers in Forests and Global Change, 2020 The impact of ecological and climatological factors on individual organisms over time and space is inherently complex and creates substantial uncertainty about how climate change will influence the global biosphere. To understand some of this complexity,
Neil Pederson +9 more
doaj +1 more source
Unprecedented acceleration of winter discharge of Upper Yenisei River inferred from tree rings
Environmental Research Letters, 2021 The Yenisei River is the largest contributor of freshwater and energy fluxes among all rivers draining to the Arctic Ocean. Modeling long-term variability of Eurasian runoff to the Arctic Ocean is complicated by the considerable variability of river ...
Irina P Panyushkina +6 more
doaj +1 more source
A new drought tipping point for conifer mortality [PDF]
, 2015 (Huang et al 2015 Environ. Res. Lett. 10 024011) present a method for predicting mortality of ponderosa pine (Pinus ponderosa) and pinyon pine (Pinus edulis) in the Southwestern US during severe drought based on the relationship between the standardized ...
Kolb, Thomas E
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Publisher Correction: Rapid 14C excursion at 3372-3371 BCE not observed at two different locations
Nature Communications, 2021 A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21647 ...
A. J. Timothy Jull +9 more
doaj +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
High temperatures constrain latewood formation in Larix gmelinii xylem in boreal forests
Global Ecology and Conservation, 2021 In trees, both radial growth and earlywood or latewood differentiation of xylem can reflect responses not only to internal stimuli but also to changes in the external environment.
Yuting Jin +5 more
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Tracing ancient solar cycles with tree rings and radiocarbon in the first millennium BCE
Nature CommunicationsThe Sun drives Earth’s energy systems, influencing weather, ocean currents, and agricultural productivity. Understanding solar variability is critical, but direct observations are limited to 400 years of sunspot records.
Nicolas Brehm +7 more
doaj +1 more source