Results 71 to 80 of about 623,719 (338)

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

Changing climate response in near-treeline bristlecone pine with elevation and aspect

Environmental Research Letters, 2014
In the White Mountains of California, eight bristlecone pine ( Pinus longaeva ) tree-ring width chronologies were developed from trees at upper treeline and just below upper treeline along North- and South-facing elevational transects from treeline to ...
Matthew W Salzer, Evan R Larson, Andrew G Bunn, Malcolm K Hughes   +3 more
doaj   +1 more source

Comparison of drought-sensitive tree-ring records from the Tien Shan of Kyrgyzstan and Xinjiang (China) during the last six centuries

Advances in Climate Change Research, 2017
In this study, tree-ring width data of Schrenk spruce (Picea schrenkiana) from the upper timberline of the Tien Shan (Kyrgyzstan) were analyzed to investigate the effect of climate change.
Hui-Qin Wang, Feng Chen, Bakytbek Ermenbaev, Rysbek Satylkanov   +3 more
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Phenological activities of cambium and inter-annual variations of Pinus densiflora saplings upon CO2 enrichment

Journal of Wood Science
The current study investigated the long-term effects of CO2 enrichment on cambial activity and wood tracheid traits of Pinus densiflora grown in Open Top Chambers (OTCs).
Jun-Hui Park, En-Bi Choi, Hyemin Lim, Jeong-Wook Seo   +3 more
doaj   +1 more source

Tree-ring evidence of the elusive 1959 summer cold event in northwestern North America

Arctic, Antarctic, and Alpine Research
Tree-ring records in northwestern North America suggest that the year 1959 was anomalously cold relative to the last several centuries. Here, we investigate the spatial characteristics, specific timing, and magnitude of the 1959 cold event through ...
Caroline Leland, Nicole Davi, Rosanne D’Arrigo, Laia Andreu-Hayles, Arturo Pacheco-Solana, Julie Edwards, Kevin J. Anchukaitis, Trevor J. Porter, Michael F.J. Pisaric, Madeleine Mant, Tracey Galloway, Rose Oelkers   +11 more
doaj   +1 more source

Unprecedented 21st century heat across the Pacific Northwest of North America

npj Climate and Atmospheric Science, 2023
Extreme summer temperatures are increasingly common across the Northern Hemisphere and inflict severe socioeconomic and biological consequences. In summer 2021, the Pacific Northwest region of North America (PNW) experienced a 2-week-long extreme ...
Karen J. Heeter, Grant L. Harley, John T. Abatzoglou, Kevin J. Anchukaitis, Edward R. Cook, Bethany L. Coulthard, Laura A. Dye, Inga K. Homfeld   +7 more
doaj   +1 more source

Matrix Model and Time-like Linear Dilaton Matter

, 2004
We consider a matrix model description of the 2d string theory whose matter part is given by a time-like linear dilaton CFT. This is equivalent to the c=1 matrix model with a deformed, but very simple fermi surface. Indeed, after a Lorentz transformation,
A. Kapustin, A. Sen, A. Sen, A. Sen, A. Strominger, A. Strominger, A.B. Zamolodchikov, B. Craps, B.C. Da Cunha, D. Gaiotto, E.J. Martinec, E.J. Martinec, F. Larsen, G.W. Moore, H. Ita, I.K. Kostov, I.R. Klebanov, I.R. Klebanov, J. Lee, J. McGreevy, J. Polchinski, J. Teschner, J. Teschner, J.L. Karczmarek, J.L. Karczmarek, J.L. Karczmarek, K. Okuyama, M. Aganagic, M. Ernebjerg, M.R. Douglas ., N. Itzhaki, N. Lambert, N. Seiberg, N. Seiberg, N. Toumbas, P. Mukhopadhyay, P.H. Ginsparg, R. Dijkgraaf, S. Alexandrov, S. Fredenhagen, S. Gukov, S. Hellerman, S. Hellerman, S.R. Das, T. Takayanagi, T. Takayanagi, T. Takayanagi, Tadashi Takayanagi, U.H. Danielsson, V. Balasubramanian, V. Fateev, V. Schomerus, X. Yin, Y. Hikida   +53 more
core   +4 more sources

Traumatic Microhemorrhages Are Not Synonymous With Axonal Injury

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diffuse axonal injury (DAI) is caused by acceleration‐deceleration forces during trauma that shear white matter tracts. Susceptibility‐weighted MRI (SWI) identifies microbleeds that are considered the radiologic hallmark of DAI and are used in clinical prognostication.
Karinn Sytsma, Rhonda Mittenzwei, Heather Maioli, Amanda Kirkland, C. Dirk Keene, Ramon Diaz‐Arrastia, Christine Mac Donald, Chiara Maffei, Brian L. Edlow, Amber L. Nolan   +9 more
wiley   +1 more source

Hip Morphology–Based Osteoarthritis Risk Prediction Models: Development and External Validation Using Individual Participant Data From the World COACH Consortium

Arthritis Care &Research, EarlyView.
Objective This study aims to develop hip morphology‐based radiographic hip osteoarthritis (RHOA) risk prediction models and investigates the added predictive value of hip morphology measurements and the generalizability to different populations. Methods We combined data from nine prospective cohort studies participating in the Worldwide Collaboration ...
Myrthe A. van den Berg, Fleur Boel, Michiel M. A. van Buuren, Noortje S. Riedstra, Jinchi Tang, Harbeer Ahedi, Nigel K. Arden, Sita M. A. Bierma‐Zeinstra, Cindy G. Boer, Flavia M. Cicuttini, Timothy F. Cootes, David T. Felson, Willem Paul Gielis, Joshua Heerey, Graeme Jones, Stefan Kluzek, Nancy E. Lane, Claudia Lindner, Joyce B. J. van Meurs, Andrea Mosler, Amanda E. Nelson, Michael C. Nevitt, Edwin H. Oei, Jos Runhaar, Harrie Weinans, Jesse H. Krijthe, Rintje Agricola   +26 more
wiley   +1 more source