Results 31 to 40 of about 1,136 (216)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Laser Photoacoustic Detection of CO2 in Old Disc Tree-Rings

open access: yesSensors, 2010
A homemade CO2–laser photoacoustic spectrometer has been used for monitoring CO2 in gas samples extracted under vacuum from the wood of old spruce disc tree-rings for a ~60 year series.
Boris Ageev   +2 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

DENDROCHRONOLOGICAL POTENTIAL OF JUNIPERUS EXCELSA (M.BIEB) FROM DRY TEMPERATE FOREST OF BALOCHISTAN PROVINCE, PAKISTAN

open access: yesFUUAST Journal of Biology, 2011
Tree-rings are widely studied for determining tree ages, growth rates and reconstruction of thé past climate. Wood samples in the form of cross-sections and cores were obtained from 50 living Juniperus excelsa trees to determine their age, growth rates ...
ATTA MOHAMMAD SARANGZAI, ALIA AHMED
doaj  

Old‐age pine trees: Unique objects of the Buzuluksky forest

open access: yesЮг России: экология, развитие
Tree‐rings contain information about variability of climatic factors and about various negative events (abnormal weather events, fires, defoliation caused by leaf‐eating insects, etc.).Due to the fact that information about climatic conditions and ...
S. E. Kucherov, P. V. Velmovskiy
doaj   +1 more source

Tracheid and Pit Dimensions Hardly Vary in the Xylem of Pinus sylvestris Under Contrasting Growing Conditions

open access: yesFrontiers in Plant Science, 2021
Maintaining sufficient water transport via the xylem is crucial for tree survival under variable environmental conditions. Both efficiency and safety of the water transport are based on the anatomical structure of conduits and their connections, the pits.
Magdalena Held   +5 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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