Results 211 to 220 of about 1,071,502 (272)

Medium Spiny Neurons Mediate Timing Perception in Coordination with Prefrontal Neurons in Primates

Advanced Science, EarlyView.
Timing perception is a crucial cognitive function enabling effective navigation in the environment, involving both prospective and retrospective timing. This study investigates the neural mechanisms in monkeys, uncovering distinct processes that shape temporal perception and highlighting the essential role of D2 medium spiny neurons in the striatum as ...
Xinhe Liu, Zhiting Zhang, Lu Gan, Panke Yu, Ji Dai   +4 more
wiley   +1 more source

Genomic Insights into Post‐Domestication Expansion and Selection of Body Size in Ponies

Advanced Science, EarlyView.
The authors’ research delves into the history of ponies by assembling a pony genome and integrating horse genomes. This unveils genetic connections between Asian and European pony breeds. Cis‐regulatory elements of key genes impacting body size are also identified.
Xingzheng Li, Zihao Wang, Min Zhu, Binhu Wang, Shaohua Teng, Jing Yan, Haoyu Wang, Pengxiang Yuan, Shuwei Cao, Xiaolu Qu, Zhen Wang, Kai Zhan, Md. Panir Choudhury, Xintong Yang, Qi Bao, Sang He, Lei Liu, Pengju Zhao, Jicai Jiang, Hai Xiang, Lingzhao Fang, Zhonglin Tang, Yuying Liao, Guoqiang Yi   +23 more
wiley   +1 more source

Phylodynamics beyond neutrality: the impact of incomplete purifying selection on viral phylogenies and inference. [PDF]

Philos Trans R Soc Lond B Biol Sci
Koelle K, Rasmussen DA.
europepmc   +1 more source

Role of Testosterone Signaling in Microglia: A Potential Role for Sex‐Related Differences in Alzheimer's Disease

Advanced Science, EarlyView.
Testosterone enhances Aβ‐induced autophagy in microglia via the non‐genomic testosterone receptor GPRC6A, promoting Aβ clearance by suppressing ERK phosphorylation and inhibiting mTOR activation. In male 5xFAD mice, testicular removal reduces microglial autophagy and Aβ clearance, which is restored by testosterone.
Haiyan Du, Akiko Mizokami, Junjun Ni, Simeng Zhang, Yosuke Yamawaki, Tomomi Sano, Eijiro Jimi, Isei Tanida, Takashi Kanematsu   +8 more
wiley   +1 more source

ZNHIT3 Regulates Translation to Ensure Cell Lineage Differentiation in Mouse Preimplantation Development

Advanced Science, EarlyView.
Box C/D snoRNP complex regulates protein translation. This study identifies ZNHIT3 as a key component of the complex and ensures normal protein expression, including transcription factors orchestrating cell fate commitment, during early mouse embryogenesis.
Guanghui Yang, Qiliang Xin, Jurrien Dean
wiley   +1 more source

Vistla: identifying influence paths with information theory. [PDF]

Bioinformatics
Kursa MB.
europepmc   +1 more source

Simultaneous Harvesting of Bipolar Plasmonic Hot Carriers for Boosting Photoconductivity in Ag Nanoprism‐Coupled Lateral Si p–n Junction

Advanced Science, EarlyView.
This study demonstrates a plasmonic hot carrier device capable of extracting both types of hot carriers simultaneously using a lateral Si p–n junction diode coupled to Ag nanoprisms. The experimental and numerical results jointly reveal precise control of the generation and injection of plasmonic hot carriers, stemming from differing injection ...
Yujin Park, Jihyang Park, Yeonghoon Jin, Yujin Roh, Hyunhwa Lee, Kyoungsik Yu, Moonsang Lee, Jeong Young Park   +7 more
wiley   +1 more source

Planning and layout of tourism and leisure facilities based on POI big data and machine learning. [PDF]

PLoS One
Wu S, Wang J, Jia Y, Yang J, Li J.
europepmc   +1 more source

Altered Neural Activity in the Mesoaccumbens Pathway Underlies Impaired Social Reward Processing in Shank3‐Deficient Rats

Advanced Science, EarlyView.
This study examines the effects of Shank3 mutation on the mesoaccumbens pathway using a Shank3‐deficient rat model. The findings reveal altered social reward processing in these rats, accompanied by changes in dopaminergic and GABAergic neural activity within the ventral tegmental area (VTA) and dopamine release in the nucleus accumbense (NAc ...
Marie Barbier, Keerthi Thirtamara Rajamani, Shai Netser, Shlomo Wagner, Hala Harony‐Nicolas   +4 more
wiley   +1 more source

Gluon scattering on the self-dual dyon. [PDF]

Lett Math Phys
Adamo T, Bogna G, Mason L, Sharma A.
europepmc   +1 more source