Results 11 to 20 of about 20,481 (222)
Characteristics of the tree shrew gut virome.
PLoS ONE, 2019 The tree shrew (Tupaia belangeri) has been proposed as an alternative laboratory animal to primates in biomedical research in recent years. However, characteristics of the tree shrew gut virome remain unclear.
Linxia Chen +11 more
doaj +4 more sources
BMC Ecology and Evolution, 2021 Background The domestication of tree shrews represents an important advance in the development of standardized laboratory animals. Little is known regarding the miRNA changes that accompany the transformation of wild tree shrews into domestic tree shrews.
Caixia Lu +6 more
doaj +1 more source
New ribotype Clostridioides difficile from ST11 group revealed higher pathogenic ability than RT078
Emerging Microbes and Infections, 2021 Clostridioides difficile is the predominant antibiotic-associated enteropathogen associated with diarrhoea or pseudomembranous colitis in patients worldwide. Previously, we identified C.
Wenpeng Gu +12 more
doaj +1 more source
Tree shrew database (TreeshrewDB): a genomic knowledge base for the Chinese tree shrew [PDF]
Scientific Reports, 2014 The tree shrew (Tupaia belangeri) is a small mammal with a close relationship to primates and it has been proposed as an alternative experimental animal to primates in biomedical research. The recent release of a high-quality Chinese tree shrew genome enables more researchers to use this species as the model animal in their studies.
Yu Fan, Dandan Yu, Yong-Gang Yao
openaire +2 more sources
Identification of glyceraldehyde 3-phosphate dehydrogenase sequence and expression profiles in tree shrew (Tupaia belangeri). [PDF]
PLoS ONE, 2014 The tree shrews (Tupaia belangeri) diverged from the primate order (Primates) and are classified as Scandentia, a separate taxonomic group of mammals.
Yu Zheng +5 more
doaj +1 more source
A Novel Tree Shrew Model of Diabetic Retinopathy. [PDF]
Front Endocrinol (Lausanne), 2021 Existing animal models with rod-dominant retinas have shown that hyperglycemia injures neurons, but it is not yet clearly understood how blue cone photoreceptors and retinal ganglion cells (RGCs) deteriorate in patients because of compromised insulin tolerance. In contrast, northern tree shrews (Tupaia Belangeri), one of the closest living relatives of
Gorbatyuk OS +8 more
europepmc +5 more sources
BMC Microbiology, 2020 Background Clostridioides difficile is a major cause of antibiotic associated diarrhea. Several animal models are used to study C. difficile infection (CDI). The tree shrew has recently been developed as a model of primate processes. C.
Wenpeng Gu +12 more
doaj +1 more source
Anatomy and nomenclature of tree shrew lymphoid tissues. [PDF]
Exp Anim, 2022 The immune response plays a key role in the disease development of the organism, while immune function serves as an important indicator for animal models evaluation. The tree shrew (Tupaia belangeri chinensis), as a new laboratory animal with a close genetic relationship with primates, has been used to construct various disease models.
Shi N +6 more
europepmc +4 more sources
CXC chemokine CXCL12 and its receptor CXCR4 in tree shrews (Tupaia belangeri): structure, expression and function. [PDF]
PLoS ONE, 2014 Chemokines are small secreted proteins functionally involved in the immune system's regulation of lymphocyte migration across numerous mammalian species.
Guiyuan Chen +8 more
doaj +1 more source
Identification of PDK4 as Hub Gene for Diabetic Nephropathy Using Co-Expression Network Analysis
Kidney & Blood Pressure Research, 2023 Introduction: Diabetic nephropathy (DN) is related to type 1 and type 2 diabetes. They are the leading cause of end-stage renal disease, but the underling specific pathogenesis of DN is not yet clear. Our study was conducted to explore how DN changed the
Yuanyuan Han +4 more
doaj +1 more source