Results 11 to 20 of about 20,283 (195)

Genome of the Chinese tree shrew [PDF]

Nature Communications, 2013
Chinese tree shrews (Tupaia belangeri chinensis) possess many features valuable in animals used as experimental models in biomedical research. Currently, there are numerous attempts to employ tree shrews as models for a variety of human disorders: depression, myopia, hepatitis B and C virus infections, and hepatocellular carcinoma, to name a few.
Fan, Yu, Huang, Zhi-Yong, Cao, Chang-Chang, Chen, Ce-Shi, Chen, Yuan-Xin, Fan, Ding-Ding, He, Jing, Hou, Hao-Long, Hu, Li, Hu, Xin-Tian, Jiang, Xuan-Ting, Lai, Ren, Lang, Yong-Shan, Liang, Bin, Liao, Sheng-Guang, Mu, Dan, Ma, Yuan-Ye, Niu, Yu-Yu, Sun, Xiao-Qing, Xia, Jin-Quan, Xiao, Jin, Xiong, Zhi-Qiang, Xu, Lin, Yang, Lan, Zhang, Yun, Zhao, Wei, Zhao, Xu-Dong, Zheng, Yong-Tang, Zhou, Ju-Min, Zhu, Ya-Bing, Zhang, Guo-Jie, Wang, Jun, Yao, Yong-Gang   +32 more
openaire   +6 more sources

Tree Shrew as an Emerging Small Animal Model for Human Viral Infection: A Recent Overview

Viruses, 2021
Viral infection is a global public health threat causing millions of deaths. A suitable small animal model is essential for viral pathogenesis and host response studies that could be used in antiviral and vaccine development.
Mohammad Enamul Hoque Kayesh, Takahiro Sanada, Michinori Kohara, Kyoko Tsukiyama-Kohara   +3 more
doaj   +3 more sources

Infectivity of Zika virus on primary cells support tree shrew as animal model

Emerging Microbes and Infections, 2019
Zika virus (ZIKV) is a mosquito-borne flavivirus that caused the public health emergency. Recently, we have proved a novel small animal tree shrew was susceptive to ZIKV infection and presented the most common rash symptoms as ZIKV patients.
Li Zhang, Zhi-Li Shen, Yue Feng, Dao-Qun Li, Na-Na Zhang, Yong-Qiang Deng, Xiao-Peng Qi, Xiao-Mei Sun, Jie-Jie Dai, Chun-Guang Yang, Zi-Feng Yang, Cheng-Feng Qin, Xue-Shan Xia   +12 more
doaj   +3 more sources

Characteristics of the tree shrew gut virome.

PLoS ONE, 2019
The tree shrew (Tupaia belangeri) has been proposed as an alternative laboratory animal to primates in biomedical research in recent years. However, characteristics of the tree shrew gut virome remain unclear.
Linxia Chen, Wenpeng Gu, Chenxiu Liu, Wenguang Wang, Na Li, Yang Chen, Caixia Lu, Xiaomei Sun, Yuanyuan Han, Dexuan Kuang, Pinfen Tong, Jiejie Dai   +11 more
doaj   +4 more sources

Identification, characterization and expression profiles of PSEN2 in the Chinese tree shrew (Tupaia belangeri chinensis) [PDF]

Journal of Integrative Neuroscience, 2020
The gene PSEN2 encodes presenilin-2, a subunit of γ-secretase. Mutations in PSEN2 are not only related to Alzheimer's disease but are also involved in other diseases.
Mingxue Li, Wenguang Wang, Dexuan Kuang, Leiying Ruan, Xiaohui Li, Xin Huang, Xiaomei Sun, Jiejie Dai, Caixia Lu
doaj   +1 more source

Comparing the hippocampal miRNA expression profiles of wild and domesticated Chinese tree shrews (Tupaia belangeri chinensis)

BMC Ecology and Evolution, 2021
Background The domestication of tree shrews represents an important advance in the development of standardized laboratory animals. Little is known regarding the miRNA changes that accompany the transformation of wild tree shrews into domestic tree shrews.
Caixia Lu, Mingxue Li, Xiaomei Sun, Na Li, Wenguang Wang, Pinfen Tong, Jiejie Dai   +6 more
doaj   +1 more source

New ribotype Clostridioides difficile from ST11 group revealed higher pathogenic ability than RT078

Emerging Microbes and Infections, 2021
Clostridioides difficile is the predominant antibiotic-associated enteropathogen associated with diarrhoea or pseudomembranous colitis in patients worldwide. Previously, we identified C.
Wenpeng Gu, Wenguang Wang, Wenge Li, Na Li, Yuanyuan Wang, Wenzhu Zhang, Caixia Lu, Pinfen Tong, Yuanyuan Han, Xiaomei Sun, Jinxing Lu, Yuan Wu, Jiejie Dai   +12 more
doaj   +1 more source

A compressed hierarchy for visual form processing in the tree shrew. [PDF]

Nature
Lanfranchi FF, Wekselblatt J, Wagenaar DA, Tsao DY.   +3 more
europepmc   +2 more sources

Selective enhancement of neural coding in V1 underlies fine-discrimination learning in tree shrew. [PDF]

Curr Biol, 2022
Schumacher JW, McCann MK, Maximov KJ, Fitzpatrick D.   +3 more
europepmc   +2 more sources

Tree shrew database (TreeshrewDB): a genomic knowledge base for the Chinese tree shrew [PDF]

Scientific Reports, 2014
The tree shrew (Tupaia belangeri) is a small mammal with a close relationship to primates and it has been proposed as an alternative experimental animal to primates in biomedical research. The recent release of a high-quality Chinese tree shrew genome enables more researchers to use this species as the model animal in their studies.
Yu Fan, Dandan Yu, Yong-Gang Yao
openaire   +2 more sources