Results 11 to 20 of about 20,445 (217)

Characteristics of the tree shrew gut virome.

PLoS ONE, 2019
The tree shrew (Tupaia belangeri) has been proposed as an alternative laboratory animal to primates in biomedical research in recent years. However, characteristics of the tree shrew gut virome remain unclear.
Linxia Chen, Wenpeng Gu, Chenxiu Liu, Wenguang Wang, Na Li, Yang Chen, Caixia Lu, Xiaomei Sun, Yuanyuan Han, Dexuan Kuang, Pinfen Tong, Jiejie Dai   +11 more
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Whole-genome DNA methylomes of tree shrew brains reveal conserved and divergent roles of DNA methylation on sex chromosome regulation [PDF]

BMC Biology
Background The tree shrew (Tupaia belangeri) is a promising emerging model organism in biomedical studies, notably due to their evolutionary proximity to primates.
Dongmin R. Son, Yifan Kong, Yulian Tan, Ting Hu, Lei Shi, Soojin V. Yi   +5 more
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Molecular Characterization and Function of the Nogo-66 Receptor (NgR1) Gene in the Chinese Tree Shrew

Journal of Integrative Neuroscience, 2023
Background: Nogo-66 receptor (NgR1) is a glycosylphosphatidylinositol-linked cell surface receptor with high affinity for Nogo-66. The binding of Nogo-66 to NgR1 plays a key role in inhibiting neurite growth, limiting synaptic plasticity and mediating ...
Caixia Lu, Xiuying Kui, Xiaofei Li, Wenguang Wang, Xiaomei Sun, Na Li, Pinfen Tong, Jiejie Dai   +7 more
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First report of Schistosoma sinensium infecting Tupaia belangeri and Tricula sp. LF

International Journal for Parasitology: Parasites and Wildlife, 2021
Schistosoma sinensium belongs to the Asian Schistosoma and is transmitted by freshwater snails of the genus Tricula. Rodents are known definitive hosts of S. sinensium.
Xuan Wang, Leiying Ruan, Qingkai Song, Wenguang Wang, Pinfen Tong, Dexuan Kuang, Caixia Lu, Na Li, Yuanyuan Han, Jiejie Dai, Xiaomei Sun   +10 more
doaj   +1 more source

Identification, characterization and expression profiles of PSEN2 in the Chinese tree shrew (Tupaia belangeri chinensis) [PDF]

Journal of Integrative Neuroscience, 2020
The gene PSEN2 encodes presenilin-2, a subunit of γ-secretase. Mutations in PSEN2 are not only related to Alzheimer's disease but are also involved in other diseases.
Mingxue Li, Wenguang Wang, Dexuan Kuang, Leiying Ruan, Xiaohui Li, Xin Huang, Xiaomei Sun, Jiejie Dai, Caixia Lu
doaj   +1 more source

Comparing the hippocampal miRNA expression profiles of wild and domesticated Chinese tree shrews (Tupaia belangeri chinensis)

BMC Ecology and Evolution, 2021
Background The domestication of tree shrews represents an important advance in the development of standardized laboratory animals. Little is known regarding the miRNA changes that accompany the transformation of wild tree shrews into domestic tree shrews.
Caixia Lu, Mingxue Li, Xiaomei Sun, Na Li, Wenguang Wang, Pinfen Tong, Jiejie Dai   +6 more
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New ribotype Clostridioides difficile from ST11 group revealed higher pathogenic ability than RT078

Emerging Microbes and Infections, 2021
Clostridioides difficile is the predominant antibiotic-associated enteropathogen associated with diarrhoea or pseudomembranous colitis in patients worldwide. Previously, we identified C.
Wenpeng Gu, Wenguang Wang, Wenge Li, Na Li, Yuanyuan Wang, Wenzhu Zhang, Caixia Lu, Pinfen Tong, Yuanyuan Han, Xiaomei Sun, Jinxing Lu, Yuan Wu, Jiejie Dai   +12 more
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Genome of the Chinese tree shrew [PDF]

Nature Communications, 2013
Chinese tree shrews (Tupaia belangeri chinensis) possess many features valuable in animals used as experimental models in biomedical research. Currently, there are numerous attempts to employ tree shrews as models for a variety of human disorders: depression, myopia, hepatitis B and C virus infections, and hepatocellular carcinoma, to name a few.
Fan, Yu, Huang, Zhi-Yong, Cao, Chang-Chang, Chen, Ce-Shi, Chen, Yuan-Xin, Fan, Ding-Ding, He, Jing, Hou, Hao-Long, Hu, Li, Hu, Xin-Tian, Jiang, Xuan-Ting, Lai, Ren, Lang, Yong-Shan, Liang, Bin, Liao, Sheng-Guang, Mu, Dan, Ma, Yuan-Ye, Niu, Yu-Yu, Sun, Xiao-Qing, Xia, Jin-Quan, Xiao, Jin, Xiong, Zhi-Qiang, Xu, Lin, Yang, Lan, Zhang, Yun, Zhao, Wei, Zhao, Xu-Dong, Zheng, Yong-Tang, Zhou, Ju-Min, Zhu, Ya-Bing, Zhang, Guo-Jie, Wang, Jun, Yao, Yong-Gang   +32 more
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Study of tree shrew biology and models: A booming and prosperous field for biomedical research [PDF]

Zoological Research
Long-Bao Lv, Bao-Ci Shan
exaly   +2 more sources

Tree shrew database (TreeshrewDB): a genomic knowledge base for the Chinese tree shrew [PDF]

Scientific Reports, 2014
The tree shrew (Tupaia belangeri) is a small mammal with a close relationship to primates and it has been proposed as an alternative experimental animal to primates in biomedical research. The recent release of a high-quality Chinese tree shrew genome enables more researchers to use this species as the model animal in their studies.
Yu Fan, Dandan Yu, Yong-Gang Yao
openaire   +2 more sources