A Porphyrin Nanomaterial for Photoimmunotherapy for Treatment of Melanoma
The TPC@OVA NPs are developed as dual‐functional nanomaterials combining phototherapy and immunotherapy for melanoma treatment. This system effectively ablates primary tumors, induces immunogenic cell death, promotes dendritic cell maturation, and enhances T cell activation.
Zhuang Fan+6 more
wiley +1 more source
Systemic Reduction of Functionally Suppressive CD4dimCD25highFoxp3+ Tregs in Human Second Trimester Pregnancy Is Induced by Progesterone and 17β-Estradiol [PDF]
Jenny Mjösberg+10 more
openalex +1 more source
Engineering the Immune Response to Biomaterials
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam+12 more
wiley +1 more source
Dynamics of peripheral tolerance and immune regulation mediated by Treg [PDF]
Shimon Sakaguchi+2 more
openalex +1 more source
The dual role of tissue regulatory T cells in tissue repair: return to homeostasis or fibrosis. [PDF]
Zhang P, Wang J, Miao J, Zhu P.
europepmc +1 more source
Therapeutic Black Phosphorus Nanosheets Elicit Neutrophil Response for Enhanced Tumor Suppression
This study explores black phosphorus (BP) nanosheets in breast cancer models, showing their ability to inhibit tumor growth. BP‐PEG enhances immune responses by promoting neutrophil recruitment and reprogramming tumor‐associated neutrophils to an antitumor phenotype, boosting both innate and adaptive antitumor immune activities.
Jing Wang+10 more
wiley +1 more source
Human CD8+CXCR3+ T cells have the same function as murine CD8+CD122+ Treg [PDF]
Zhe Shi+6 more
openalex +1 more source
Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients. [PDF]
Wen Y, Zhao J, Zhang Z.
europepmc +1 more source
A self‐assembled peptide (NF‐1) targeting tumor cell Golgi apparatus (GA) is tailored for effective immunotherapy via reshaping the MIF‐mediated immunosuppressive network. After targeting tumor cell GA, the morphology of NF‐1 is changed from micelles to nano‐fibers under the action of furin, thus inducing cell apoptosis as well as GA dysfunction ...
Xiang Li+7 more
wiley +1 more source
CD38-mediated metabolic reprogramming promotes the stability and suppressive function of regulatory T cells in tumor. [PDF]
Sarkar I+16 more
europepmc +1 more source