Results 261 to 270 of about 203,023 (389)
Western Diet Dampens T Regulatory Cell Function to Fuel Hepatic Inflammation in Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]
Chaudhary S +10 more
europepmc +1 more source
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen +12 more
wiley +1 more source
Cancer Immunomodulatory Effect of <i>Bidens pilosa</i> L. in Mice: Suppression of Tumor-Associated Macrophages and Regulatory T Cells. [PDF]
Zhu M +10 more
europepmc +1 more source
The schematic illustration of the MHSCG platform for spatiotemporal responsive GRb1 release to induce androgen deprivation therapy (ADT) and immunogenic cell death (ICD) multimodal therapy in prostate cancer. Abstract Metal‐based immunotherapy represents a promising strategy for enhancing antitumor efficacy; however, its clinical application is limited
Rui Zan +13 more
wiley +1 more source
Combinatorial Analysis of CD4<sup>+</sup>Tregs, CD8<sup>+</sup>Teffs, and Inflammatory Indices Predict Response to ICI in ES-SCLC Patients. [PDF]
Xagara A +17 more
europepmc +1 more source
CD4+CD25+ Treg cells inhibit human memory γδ T cells to produce IFN-γ in response to M tuberculosis antigen ESAT-6 [PDF]
Li Li, Changyou Wu
openalex +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
B Lymphocytes Impede Tregs to Erode Islet Tolerance in Type 1 Diabetes. [PDF]
Wilson CS, Stocks BT, Falk AC, Moore DJ.
europepmc +1 more source

