Results 261 to 270 of about 130,982 (298)

Decoding Blastocystis‐Driven Mechanisms in Gut Microbiota and Host Metabolism

Advanced Science, Volume 12, Issue 17, May 8, 2025.
Blastocystis, a prevalent gut microbe, interacts with the host through metabolic and immune pathways, influencing cardiometabolic health. This perspective explores its role in modulating short‐chain fatty acid production, tryptophan metabolism, and immune signaling, potentially impacting cholesterol absorption, glucose metabolism, and vascular health ...
Lei Deng, Kevin SW Tan
wiley   +1 more source

Long noncoding RNA BCYRN1 promotes cardioprotection by enhancing human and murine regulatory T cell dynamics. [PDF]

J Clin Invest
Liao K, Yu J, Akhmerov A, Mohammadigoldar Z, Li L, Liu W, Anders N, Ibrahim AG, Marbán E.   +8 more
europepmc   +1 more source

Targeted STING Activation Using Modified Ultrasound‐Responsive Microbubbles Enhances Immune Checkpoint Blockade Against Melanoma

Advanced Science, EarlyView.
This study explores the use of ultrasound contrast agents loaded with Stimulator of Interferon Genes (STING) agonists as an approach to activate the body's immune system against cancer. Termed Microbubble‐assisted UltraSound‐guided Immunotherapy of Cancer (MUSIC), this strategy effectively inhibits tumor growth and improves survival in mouse models of ...
Sina Khorsandi, Kristin Huntoon, Yifan Wang, Adam Woodward, Abin Antony, Connor Endsley, Nazia Hafeez, Jared L. Edwards, Nicole McCuen, Prasanna G. Alluri, Betty Y.S. Kim, Wen Jiang, Jacques Lux   +12 more
wiley   +1 more source

Differential Responses of Human Regulatory T Cells (Treg) and Effector T Cells to Rapamycin

, 2009
Laura Strauss, Malgorzata Czystowska, Marta Szajnik, Magis Mandapathil, Theresa L. Whiteside   +4 more
openalex   +2 more sources

The distinctive signature of regulatory CD4 T cells committed in the human thymus. [PDF]

Front Immunol
Raposo AASF, Paço S, Ângelo-Dias M, Rosmaninho P, Almeida ARM, Sousa AE.   +5 more
europepmc   +1 more source

Engineered Probiotics Mitigate Gut Barrier Dysfunction Induced by Nanoplastics

Advanced Science, EarlyView.
Intestinal barrier stability is vital for gut health. Plastic polyethylene terephthalate (PET) disrupts this barrier, causing inflammation and infections. This study encodes transforming growth factor‐β into EcN and modifies its surface with pH‐responsive polymer (EcNT@L), creating an oral drug delivery system to repair nano PET‐induced intestinal ...
Wenxin Chen, Qiyan Guo, Hong Li, Xue Chi, Xiang Ma, Yanqiong Tang, Quanfeng Liang, Zhu Liu, Yong Liu, Juanjuan Li   +9 more
wiley   +1 more source

Role of Peripheral Blood Regulatory T Cells and IL-2 in the Collateral Circulation of Acute Ischemic Stroke. [PDF]

Int J Gen Med
Zhang S, Rao C, Wen M, Zhang X, Zha Z, Gu T, Zhu L, Yu C.   +7 more
europepmc   +1 more source

Plac1+ Tumor Cell‐Treg Interplay Supports Tumorigenesis and Progression of Head and Neck Cancer

Advanced Science, Volume 12, Issue 17, May 8, 2025.
Meng et al. screen genes in the CTAs family and find Plac1 is specifically expressed in head and neck squamous cell carcinoma (HNSCC) cells. They reveal that Plac1 expression promotes HNSCC progression directly by activating PI3K/AKT signaling pathway.
Xiaoyan Meng, Zhonglong Liu, Lu Zhao, Ran Li, Luoman Gan, Liren Cao, Jingjing Sun, Lingfang Zhang, Yue He   +8 more
wiley   +1 more source

Identification of the Molecular Subtype and Prognostic Characteristics of Breast Cancer Based on Tumor-Infiltrating Regulatory T Cells. [PDF]

Breast J
Ma J, Hu G, Kuang L, Zhu Z.
europepmc   +1 more source

Effect of Extracellular Vesicles Derived From Tumor Cells on Immune Evasion

Advanced Science, Volume 12, Issue 12, March 27, 2025.
Immunity and cancer interplay are central to tumor progression. This review explores how tumor cells exploit extracellular vesicles (EVs) to orchestrate immune evasion. Tumor‐derived EVs (TEVs) transport immunomodulatory cargo to shape immune differentiation, activation, and function.
Xuanfan Liu, Kenneth K.W. To, Qinsong Zeng, Liwu Fu   +3 more
wiley   +1 more source