Results 121 to 130 of about 55,627 (244)

Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 9, September 2026.
Regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy‐dependent cell death, interact with mitochondrial dysfunction, proteostasis failure, lysosomal stress, glial remodeling, and neuroinflammation across major neurodegenerative diseases.
Tianjiao Li, Qian Zhang, Yichen Wu, Ruixue Huang   +3 more
wiley   +1 more source

Evolutionary Analysis of Trehalose Breakdown Pathways. [PDF]

Genome Biol Evol
Muthu G G, Laxman S, Seshasayee ASN.
europepmc   +1 more source

Conformational determinants of glucagon stability and aggregation kinetics in aqueous and commercial formulations

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Glucagon is a well‐established therapeutic peptide, widely used to treat hypoglycemia. Like many peptide drugs, it offers advantages such as specificity, biocompatibility, and high affinity for receptor targets, but suffers from limited physical and chemical stability.
Angelo Santoro, Marco Macis, Michela Buonocore, Antonio Ricci, Anna Maria D'Ursi   +4 more
wiley   +1 more source

Improving the post-oculoplastic tear film: trehalose as a critical adjunct. [PDF]

Int J Ophthalmol
Arslan N, Kakil ŞB, Çoban A.
europepmc   +1 more source

The Mycobacterium tuberculosis Rv0132c Gene Product Mtb‐FGD2 Can Act as an F420‐Dependent Glucose Dehydrogenase

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 9, Page 1610-1627, September 2026.
ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi, Matthew Snee, Richard B. Tunnicliffe, Linus O. Johanissen, Matthew J. Cliff, Colin W. Levy, Derren J. Heyes, Marina Golovanova, Thomas A. Jowitt, Sam Hay, Andrew W. Munro, Jonathan P. Waltho, David Leys   +12 more
wiley   +1 more source

Bifunctional trehalase FsTreA coordinates intracellular mobilization and extracellular utilization of trehalose to modulate virulence in <i>Fusarium sacchari</i>. [PDF]

Appl Environ Microbiol
Chen Y, Zhao Y, Cheng G, Lin Y, Liang Q, Zhu L, Huang L, Lin X, Yao Z, Zou C.   +9 more
europepmc   +1 more source

Effects of pupal hypoxia duration and holding temperature on quality control parameters of sterile Queensland fruit fly

Pest Management Science, Volume 82, Issue 9, Page 8382-8391, September 2026.
Queensland fruit fly pupae tolerate hypoxia up to 2 days without compromising quality. Prolonged hypoxia, especially at 25 °C, reduces emergence and flight ability. Storage at 18 °C is recommended. Abstract BACKGROUND The sterile insect technique is used to eradicate outbreaks of Queensland fruit fly (Q‐fly) Bactrocera tryoni (Froggatt) in fruit‐fly ...
Sushil K. Gaire, Saluna Pokhrel, Polychronis Rempoulakis, Phillip W. Taylor, Bishwo P. Mainali   +4 more
wiley   +1 more source

Trehalose: a multifunctional sugar and its metabolites are biotechnological targets for crop salinity tolerance under saline conditions. [PDF]

Plant Mol Biol
Mansour MMF, Hassan FAS.
europepmc   +1 more source

Genome–phenome association prediction using weighted deep matrix factorization with a multisource graph attention network

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Genome–phenome association (GPA) prediction can broaden the understanding of biological mechanisms underlying complex phenotypic traits (e.g., diseases and agronomic traits). Traditional deep matrix factorization (DMF)‐based GPA methods can integrate multiple data types and uncover nonlinear associations but often rely on low‐dimensional ...
Ran Duan, Wei Cao, Maozu Guo, Le Tian, Lingling Zhao   +4 more
wiley   +1 more source

Development and Characterization of a Stable Oil-in-Water Nanoemulsion Using Impingement Jet Mixing and Lyophilization Techniques. [PDF]

Pharmaceutics
Shao A, Zhang J, Jin Z, Li Y, Tang J, Chen Q, Wu H, Guo J.   +7 more
europepmc   +1 more source