Results 121 to 130 of about 74,026 (260)
British Journal of Pharmacology, EarlyView.Background and Purpose Atherosclerosis, a chronic inflammatory disease characterised by lipid accumulation and endothelial dysfunction, remains a leading cause of cardiovascular morbidity and mortality. While cannabinoid 2 (CB2) receptor agonists show therapeutic promise in preclinical studies, their systemic application is hindered by poor ...
Lucía Martín‐Navarro +3 more
wiley +1 more source
Ecological Entomology, EarlyView.Hamiltonella defensa infection increases honeydew production in certain aphid genotypes, potentially modifying aphid feeding behaviour. Parasitoid wasps, Aphidius ervi, are more attracted to honeydew from H. defensa‐infected aphids; though larger honeydew amounts may slightly deter searching.
Desiré Macheda +5 more
wiley +1 more source
Schematic showing the two-step synthesis of trehalose.
, 2014 Trehalose is made in a two-step process catalyzed by trehalose-6-phosphate synthase (TPS) and trehalose-6-phosphate phosphatase (T6PP).
Debra Dunaway-Mariano (592218) +12 more
core +1 more source
Circadian rhythms of metabolite abundance in Drosophila are largely driven by time of feeding
The FEBS Journal, EarlyView.Circadian clocks exist in the brain and peripheral tissues such as the Drosophila fat body. Single‐nuclei transcriptomics reveal that the fat body clock generates time‐of‐day differences in metabolic gene transcription, which may also be indirectly controlled by brain clocks.
Sumit Saurabh +7 more
wiley +1 more source
Intracellular Protective Functions and Therapeutical Potential of Trehalose
MoleculesTrehalose is a naturally occurring, non-reducing saccharide widely distributed in nature. Over the years, research on trehalose has revealed that this initially thought simple storage molecule is a multifunctional and multitasking compound protecting ...
Dorota Kuczyńska-Wiśnik +2 more
doaj +1 more source
Common pathways and outliers in glucose catabolism across Trypanosomatidae
The FEBS Journal, EarlyView.Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes +5 more
wiley +1 more source
Current Opinion in Plant Biology, 2007 Trehalose 6-phosphate (T6P) is a sugar signal of emerging significance. It is an essential component of the mechanisms that coordinate metabolism with plant growth adaptation and development. Its significance began to dawn when genetic modification of the trehalose pathway produced dramatic phenotypes, before the genetic proliferation of the trehalose ...
openaire +2 more sources
Insect Molecular Biology, EarlyView.TcFur1, a furin 1 ortholog in Tribolium castaneum, is highly expressed in pupae and declines in adults. TcFur1 knockdown reduces oviposition but does not alter triacylglycerol levels or total lipase activity. TcFur1 knockdown increases circulating trehalose and decreases expression of insulin‐like peptides and the AKH receptor.
Julia Sanches‐Almeida +2 more
wiley +1 more source
Journal of Fish Biology, EarlyView.Abstract We used an ecological niche theory framework integrating physiological and behavioural ecology to understand interspecific differentiation of juveniles of four Antarctic fishes: Trematomus bernacchii, Trematomus pennellii, Trematomus nicolai and Pagothenia borchgrevinki.
Amanda J. Frazier +5 more
wiley +1 more source
, 2010 Carboxymethyl alpha,alpha-trehalose (CMT) and a quaternary ammonium derivative of alpha,alpha-trehalose (QT) were successfully prepared, and their moisture absorption and retention activities were assessed.
Qin, Song +6 more
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