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Trehalose in Water Revisited

The Journal of Physical Chemistry B, 2018
Trehalose, commonly found in living organisms, is believed to help them survive severe environmental conditions, such as drought or extreme temperatures. With the aim of trying to understand these properties, two recent neutron scattering studies investigate the structure of trehalose water solutions but come to seemingly opposite conclusions.
Alan K. Soper   +4 more
openaire   +3 more sources

Immobilization of thermostable trehalose synthase for the production of trehalose

Enzyme and Microbial Technology, 2006
Screening of several immobilization carriers for trehalose synthase (TSase) from Thermus caldophilus GK24 has been performed for the efficient production of trehalose from maltose. This is the first report on immobilization of recombinant TSase for the production of trehalose.
Youn-Jeung Cho   +2 more
openaire   +1 more source

Engineering the acceptor specificity of trehalose phosphorylase for the production of trehalose analogs

Biotechnology Progress, 2012
AbstractTrehalose (α‐D‐glucopyranosyl‐(1,1)‐α‐D‐glucopyranoside) is widely used in the food industry, thanks to its protective effect against freezing and dehydration. Analogs of trehalose have the additional benefit that they are not digested and thus do not contribute to our caloric intake.
Van der Borght, Jef   +2 more
openaire   +2 more sources

Synthesis of trehalose glycolipids

Organic & Biomolecular Chemistry, 2020
Chemical synthesis of trehalose glycolipids such as DAT, TDM, SL-1, SL-3, and Ac 2 SGL from MTb, emmyguyacins from fungi, succinoyl trehalose from rhodococcus, and maradolipids from worms, as well as mycobacterial oligosaccharides is reviewed.
Santanu Jana, Suvarn S. Kulkarni
openaire   +2 more sources

Trehalose and Protein Stability

Current Protocols in Protein Science, 2010
AbstractThe role of osmolytes, and especially trehalose, in stabilizing proteins under stress conditions is now a widely accepted fact. The physical and chemical properties of trehalose, i.e., low chemical reactivity, nonreducing nature, high glass transition temperature, high affinity for water molecules, existence of a number of polymorphs, etc ...
Nishant Kumar, Jain, Ipsita, Roy
openaire   +2 more sources

Trehalose mimetics as inhibitors of trehalose processing enzymes

2011
This report aims at giving a broad overview on biological roles of trehalose, on trehalose processing enzymes and on the use of trehalose mimetics as biological probes and/or enzyme inhibitors for therapeutical ...
BINI, DAVIDE   +4 more
openaire   +2 more sources

In-Situ Biocatalytic Production of Trehalose with Autoinduction Expression of Trehalose Synthase

Journal of Agricultural and Food Chemistry, 2018
We developed an in-situ biocatalytic process that couples autoinduction expression of trehalose synthase (TreS) and whole-cell catalysis for trehalose production. With lactose as the autoinducer, the activity of recombinant TreS in recombinant Escherichia coli was optimized through a visualization method, which resulted in a maximum value of 12 033 ...
Xincheng Yan   +5 more
openaire   +2 more sources

A process for production of trehalose by recombinant trehalose synthase and its purification

Enzyme and Microbial Technology, 2018
The process for production of trehalose using trehalose synthase (TreS) to convert maltose into trehalose in one step is highly desirable in the industry. Nonetheless, the studies on industrial-scale production of trehalose by recombinant TreS in Escherichia coli are still scarce. In this study, a TreS from Pseudomonas putida ATCC47054 was expressed in
HongLing, Liu   +4 more
openaire   +2 more sources

Enzymatic Production of Trehalose and Trehalulose by Immobilized Thermostable Trehalose Synthase

Journal of Agricultural and Food Chemistry
Trehalose, a versatile disaccharide renowned for its unique physical and chemical properties, finds extensive application in the food, pharmaceutical, and cosmetic industries. While conventional extraction methods face challenges, enzymatic conversion offers a promising avenue for the industrial production of trehalose.
Zi-Ling Yong   +3 more
openaire   +2 more sources

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