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Trehalose synthase converts glycogen to trehalose
The FEBS Journal, 2008Trehalose (α,α‐1,1‐glucosyl‐glucose) is essential for the growth of mycobacteria, and these organisms have three different pathways that can produce trehalose. One pathway involves the enzyme described in the present study, trehalose synthase (TreS), which interconverts trehalose and maltose.
Yuan-Tseng, Pan +5 more
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Systematic and Applied Microbiology, 1988
Summary The non-reducing disaccharide trehalose (α-D-glucopyranosyl-α-D-glucopyranoside) was identified in Sulfolobus solfataricus by 13C NMR spectroscopy. The screening of a range of other archaebacteria, using a rapid isolation and purification procedure for trehalose, indicated that this disaccharide is present in a number of halophilic ...
B. NICOLAUS +5 more
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Summary The non-reducing disaccharide trehalose (α-D-glucopyranosyl-α-D-glucopyranoside) was identified in Sulfolobus solfataricus by 13C NMR spectroscopy. The screening of a range of other archaebacteria, using a rapid isolation and purification procedure for trehalose, indicated that this disaccharide is present in a number of halophilic ...
B. NICOLAUS +5 more
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Trehalose metabolism in plants [PDF]
Plant Journal, 2014 SummaryTrehalose is a quantitatively important compatible solute and stress protectant in many organisms, including green algae and primitive plants. These functions have largely been replaced by sucrose in vascular plants, and trehalose metabolism has taken on new roles.
John E. Lunn +2 more
exaly +5 more sources
Trehalose transporter 1, a facilitated and high-capacity trehalose transporter, allows exogenous trehalose uptake into cells [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2007 Trehalose is potentially a useful cryo- or anhydroprotectant molecule for cells and biomolecules such as proteins and nucleotides. A major obstacle to application is that cellular membranes are impermeable to trehalose. In this study, we isolated and characterized the functions of a facilitated trehalose transporter [trehalose transporter ...
Takahiro Kikawada
exaly +3 more sources
Strategies for desymmetrising trehalose to synthesise trehalose glycolipids
Org. Biomol. Chem., 2014The desymmetrisation and regioselective protection of trehalose are major challenges in the chemical synthesis of biologically essential trehalose glycolipids.
Chia-Hui, Wu, Cheng-Chung, Wang
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Trehalose amorphization and recrystallization
Carbohydrate Research, 2008The stability of the amorphous trehalose prepared by using several procedures is presented and discussed. Amorphization is shown to occur by melting (T(m)=215 degrees C) or milling (room temperature) the crystalline anhydrous form TRE-beta. Fast dehydration of the di-hydrate crystalline polymorph, TRE-h, also produces an amorphous phase.
CESARO, ATTILIO, SUSSICH F.
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Synthesis of trehalose glycolipids
Organic & Biomolecular Chemistry, 2020Chemical synthesis of trehalose glycolipids such as DAT, TDM, SL-1, SL-3, and Ac2SGL from MTb, emmyguyacins from fungi, succinoyl trehalose from rhodococcus, and maradolipids from worms, as well as mycobacterial oligosaccharides is reviewed.
Santanu Jana, Suvarn S. Kulkarni
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The Journal of Physical Chemistry B, 2018
Trehalose, commonly found in living organisms, is believed to help them survive severe environmental conditions, such as drought or extreme temperatures. With the aim of trying to understand these properties, two recent neutron scattering studies investigate the structure of trehalose water solutions but come to seemingly opposite conclusions.
Alan K. Soper +4 more
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Trehalose, commonly found in living organisms, is believed to help them survive severe environmental conditions, such as drought or extreme temperatures. With the aim of trying to understand these properties, two recent neutron scattering studies investigate the structure of trehalose water solutions but come to seemingly opposite conclusions.
Alan K. Soper +4 more
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Trehalose and Protein Stability
Current Protocols in Protein Science, 2010AbstractThe role of osmolytes, and especially trehalose, in stabilizing proteins under stress conditions is now a widely accepted fact. The physical and chemical properties of trehalose, i.e., low chemical reactivity, nonreducing nature, high glass transition temperature, high affinity for water molecules, existence of a number of polymorphs, etc ...
Nishant Kumar, Jain, Ipsita, Roy
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Mono- and dialdehyde of trehalose: new synthons to prepare trehalose bio-conjugates
Organic & Biomolecular Chemistry, 2021Direct conversion of unprotected trehalose into the corresponding mono- or dialdehyde provides easy access to various trehalose analogues/bioconjugates.
Valentina Greco +2 more
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