Results 61 to 70 of about 17,765 (261)
The Materials to the Porthmion Chronology
The Bosporus expedition of the Institute for the History of Material Culture of the Russian Academy of Sciences conducted a small archaeological research in the northwestern sector of Porthmion in 2002–2003.
Roman V. Stoyanov
doaj +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The Jining River northern margin fault is a newly discovered Quaternary active fault, located at the junction of the northeastern corner of the Ordos Block and the Yinshan-Yanshan Uplift (Jining District, Ulanqab, Inner Mongolia). The northeastern margin
Haowen Ma, Shaopeng Dong
doaj +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Effects of Landslides on the Safety of Roads and Rural Settlements in Iran and Stabilization Methods (Case Study of Naghan-Karoon 4 Road Landslides) [PDF]
This study investigates landslides occurred in Chahar Mahal – Bakhtiari Province in Iran, using a probability analysis for describing landslide mechanism. Two case studies of landslide in this province (Naghan – karoon 4 Road) are analyzed using software
Mohsen Salehi +3 more
doaj
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
In the article, the results of the temperature of the autonomous helio-greenhouse of the trench type in the abnormal cold climatic conditions of Uzbekistan are discussed.
Bozorbek Botirov +4 more
doaj +1 more source

