Results 81 to 90 of about 56,487 (246)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
First demonstration of single trench fiber for delocalization of higher order modes
We demonstrate an ytterbium-doped single-trench fiber ensuring a high losses ratio (~1000) and low power fraction (~0.7) between the higher-order-modes and fundamental-mode with excellent bend robustness and 85% laser efficiency at a wavelength of ...
Baskiotis, C. +3 more
core +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Applied SciencesThe Jining River northern margin fault is a newly discovered Quaternary active fault, located at the junction of the northeastern corner of the Ordos Block and the Yinshan-Yanshan Uplift (Jining District, Ulanqab, Inner Mongolia). The northeastern margin
Haowen Ma, Shaopeng Dong
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Effects of Landslides on the Safety of Roads and Rural Settlements in Iran and Stabilization Methods (Case Study of Naghan-Karoon 4 Road Landslides) [PDF]
مسکن و محیط روستا, 2017 This study investigates landslides occurred in Chahar Mahal – Bakhtiari Province in Iran, using a probability analysis for describing landslide mechanism. Two case studies of landslide in this province (Naghan – karoon 4 Road) are analyzed using software
Mohsen Salehi +3 more
doaj
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Proceedings of the International Conference on Applied Innovations in ITIn the article, the results of the temperature of the autonomous helio-greenhouse of the trench type in the abnormal cold climatic conditions of Uzbekistan are discussed.
Bozorbek Botirov +4 more
doaj +1 more source