Results 61 to 70 of about 56,487 (246)
Des chevaux sous l’Occupation : le charnier du site archéologique des Varennes à Bar-sur-Aube (Aube)
Horses under the Occupation, the mass grave at the Varennes archaeological at Bar-sur-Aube (Aube). The discovery in 2013, at Bar-sur-Aube of a trench filled with more than forty carcasses of horses, led the team of archaeologists who made this discovery ...
Gilles Deborde
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Improvement of bearing capacity of footings using reinforced granular trench
Recent evidence suggests that the stability performance of footings can be greatly enhanced using a granular trench. Therefore, this paper sets out to study the bearing capacity of strip footing on a two-layered soil system that is composed of overlying ...
Bhattacharya, Paramita +2 more
core +1 more source
Necking Reduction at Low Temperature in Aspect Ratio Etching of SiO2 at CF4/H2/Ar Plasma
This study investigated the effect of temperature on the aspect-ratio etching of SiO2 in CF4/H2/Ar plasma using patterned samples of a 200 nm trench in a low-temperature reactive-ion etching system.
Hee-Tae Kwon +10 more
doaj +1 more source
This study is aimed at investigating the effect of various tractor ride conditions on the lumbar spine during rotavator operation. The lumbar spinal response was assessed by determining static compressive dose, i.e., Sed (8).
Amandeep Singh +5 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The article considers the issue of choosing the optimal construction arrangement of cable lines with a voltage of 10 (20, 35) kV with cross-linked polyethylene insulation.
M. E. Vysotski
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

