Results 61 to 70 of about 56,487 (246)

Des chevaux sous l’Occupation : le charnier du site archéologique des Varennes à Bar-sur-Aube (Aube)

open access: yesIn Situ, 2015
Horses under the Occupation, the mass grave at the Varennes archaeological at Bar-sur-Aube (Aube). The discovery in 2013, at Bar-sur-Aube of a trench filled with more than forty carcasses of horses, led the team of archaeologists who made this discovery ...
Gilles Deborde
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Improvement of bearing capacity of footings using reinforced granular trench

open access: yes, 2021
Recent evidence suggests that the stability performance of footings can be greatly enhanced using a granular trench. Therefore, this paper sets out to study the bearing capacity of strip footing on a two-layered soil system that is composed of overlying ...
Bhattacharya, Paramita   +2 more
core   +1 more source

Necking Reduction at Low Temperature in Aspect Ratio Etching of SiO2 at CF4/H2/Ar Plasma

open access: yesNanomaterials
This study investigated the effect of temperature on the aspect-ratio etching of SiO2 in CF4/H2/Ar plasma using patterned samples of a 200 nm trench in a low-temperature reactive-ion etching system.
Hee-Tae Kwon   +10 more
doaj   +1 more source

Whole Body Vibration Exposure among the Tractor Operator during Soil Tillage Operation: An Evaluation using ISO 2631-5 Standard

open access: yesShock and Vibration, 2022
This study is aimed at investigating the effect of various tractor ride conditions on the lumbar spine during rotavator operation. The lumbar spinal response was assessed by determining static compressive dose, i.e., Sed (8).
Amandeep Singh   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

The Choice of a Construction Arrangement for Cable Lines with a Voltage of 10 kV According to the Criterion of the Minimum Expected Cost

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика
The article considers the issue of choosing the optimal construction arrangement  of cable lines with a voltage of 10 (20, 35) kV with cross-linked polyethylene insulation.
M. E. Vysotski
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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