Results 111 to 120 of about 6,114,826 (359)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Replacing the Concept of Externalities to Analyze Constraints on Global Economic Growth and Move Toward a New Economic Paradigm

Cadmus, 2014
The prevailing economic paradigm has fallen short as a guide to policy making in this era of global economic crises. Numerous efforts are underway to revise it or replace it with a science of society that integrates intellectual disciplines.
Jim Lunday
doaj  

Aberrant recovery of timescale-aligned amplitude balance links to symptoms and cognition in schizophrenia

Translational Psychiatry
Schizophrenia involves well-documented disruptions of large-scale brain coordination, but how strongly networks engage one another, and how that engagement recovers when disrupted, remains poorly understood.
Sir-Lord Wiafe, Spencer Kinsey, Najme Soleimani, Raymond O. Nsafoa, Nigar Khasayeva, Amritha Harikumar, Robyn Miller, Vince D. Calhoun   +7 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Heat transfer enhancement in free convection flow of CNTs Maxwell nanofluids with four different types of molecular liquids

Scientific Reports, 2017
This article investigates heat transfer enhancement in free convection flow of Maxwell nanofluids with carbon nanotubes (CNTs) over a vertically static plate with constant wall temperature. Two kinds of CNTs i.e.
Sidra Aman, Ilyas Khan, Zulkhibri Ismail, Mohd Zuki Salleh, Qasem M. Al-Mdallal   +4 more
doaj   +1 more source

Relationship between Median Survival and Long Term Survival in Lung Cancer: a scoring method by Means of a Multivariate Analysis

, 1986
INTERNATIONAL SYMPOSIUM NEW TRENDS IN THE TREATMENT OF ADVANCED TUMORS ROME,21-22 FEBBRAIO ...
CICCONETTI, Franco, NEW TRENDS IN THE TREATMENT OF ADVANCED T.U.M.O.R.S.P.A.G. . ROMA, SERONO SYMPOSIA REVIEW NØ, STIPA, Sergio, BUTTINI G, FEBBRAIO, BARTOLI S, BOTTI C, ALEXANDER R, MODINI, Claudio   +9 more
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

A Dynamic Entropy Approach Reveals Reduced Functional Network Connectivity Trajectory Complexity in Schizophrenia

Entropy
Over the past decade and a half, dynamic functional imaging has revealed low-dimensional brain connectivity measures, identified potential common human spatial connectivity states, tracked the transition patterns of these states, and demonstrated ...
David Sutherland Blair, Robyn L. Miller, Vince D. Calhoun   +2 more
doaj   +1 more source

Becoming a guide for pilgrims in a time of secularization

Church, Communication and Culture, 2018
The goal of this case study is threefold: first, to introduce the concept of postmodern pilgrim, leveraging on two pilgrimage experiences in Switzerland; second, to propose a model (PEARL) for developing training modules for pilgrim guides; and finally ...
Terry Inglese
doaj   +1 more source

Statistical Power for Trend-in-trend Design [PDF]

Epidemiology, 2018
Ashkan, Ertefaie, Dylan S, Small, Xinyao, Ji, Charles, Leonard, Sean, Hennessy   +4 more
openaire   +2 more sources