Results 71 to 80 of about 2,439,891 (316)

Self-supervised multimodal learning for group inferences from MRI data: Discovering disorder-relevant brain regions and multimodal links

NeuroImage
In recent years, deep learning approaches have gained significant attention in predicting brain disorders using neuroimaging data. However, conventional methods often rely on single-modality data and supervised models, which provide only a limited ...
Alex Fedorov, Eloy Geenjaar, Lei Wu, Tristan Sylvain, Thomas P. DeRamus, Margaux Luck, Maria Misiura, Girish Mittapalle, R. Devon Hjelm, Sergey M. Plis, Vince D. Calhoun   +10 more
doaj   +1 more source

Recombinant Hepatitis B surface antigen vaccines for the delivery of disease-related antigens.

, 2008
The extraordinary immunogenicity of the envelope protein of Hepatitis B virus (HBsAg) has been exploited to derive the pan-global vaccine to prevent Hepatitis B virus infection.
Scott Thomson, Tindle, Robert W., Gould, Allan R., Oscar Haigh   +3 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Becoming a guide for pilgrims in a time of secularization

Church, Communication and Culture, 2018
The goal of this case study is threefold: first, to introduce the concept of postmodern pilgrim, leveraging on two pilgrimage experiences in Switzerland; second, to propose a model (PEARL) for developing training modules for pilgrim guides; and finally ...
Terry Inglese
doaj   +1 more source

Patterns & Trends

, 1982
vii,153 hlm.;22 ...
Patterns & Trends
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Relationship between Median Survival and Long Term Survival in Lung Cancer: a scoring method by Means of a Multivariate Analysis

, 1986
INTERNATIONAL SYMPOSIUM NEW TRENDS IN THE TREATMENT OF ADVANCED TUMORS ROME,21-22 FEBBRAIO ...
CICCONETTI, Franco, NEW TRENDS IN THE TREATMENT OF ADVANCED T.U.M.O.R.S.P.A.G. . ROMA, SERONO SYMPOSIA REVIEW NØ, STIPA, Sergio, BUTTINI G, FEBBRAIO, BARTOLI S, BOTTI C, ALEXANDER R, MODINI, Claudio   +9 more
core  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Replacing the Concept of Externalities to Analyze Constraints on Global Economic Growth and Move Toward a New Economic Paradigm

Cadmus, 2014
The prevailing economic paradigm has fallen short as a guide to policy making in this era of global economic crises. Numerous efforts are underway to revise it or replace it with a science of society that integrates intellectual disciplines.
Jim Lunday
doaj