Results 61 to 70 of about 3,613 (152)

Ultrasmall Au10–12 Nanoclusters: A Novel Platform for 223Ra‐Targeted Tumor α‐Therapy

Exploration, Volume 6, Issue 2, April 2026.
Encapsulating 223Ra in Au10‐12 nanoclusters and functionalizing them with RGD peptides enables targeted α‐therapy and immune microenvironment remodeling in non‐osseous tumors like triple‐negative breast cancer. This study establishes a foundational framework for novel 223Ra‐labeled α‐radiopharmaceuticals and shows strong potential for clinical ...
Yifei Jiang, Huizhen Yang, Guoping Jia, Wangxi Hai, Rongyi Huang, Peng Wang, Min Zhang, Danni Li, Yizhou Chen, Xiao Li, Biao Li, Chunfu Zhang   +11 more
wiley   +1 more source

Focal Spot, Winter 2009/2010 [PDF]

, 2010
https://digitalcommons.wustl.edu/focal_spot_archives/1113/thumbnail ...

core   +1 more source

Cyclic 2.5D Perceptual Loss for Cross‐Modal 3D Medical Image Synthesis: T1w MRI to Tau PET

Human Brain Mapping, Volume 47, Issue 5, 1 April 2026.
ABSTRACT Positron emission tomography (PET) provides an in vivo molecular marker for various diseases, including Alzheimer's disease and related dementias (ADRD). PET has become increasingly integrated into diagnostic decision‐making, disease staging, and clinical trial enrichment.
Junho Moon, Symac Kim, Haejun Chung, Ikbeom Jang, Alzheimer's Disease Neuroimaging Initiative   +4 more
wiley   +1 more source

Dynamic Alterations of Functional Systems in Alzheimer's Disease: A Co‐Activation Pattern Analysis

Human Brain Mapping, Volume 47, Issue 5, 1 April 2026.
State 3 exhibited significantly reduced persistence and resilience in both MCI and AD compared to CU. Individuals with MCI and AD showed reduced transition probability from State 2 to State 5 and decreased self‐transitions in State 3. Graph theoretical results corresponded well to the findings of the above CAP analysis.
Pan Wang, Mengfan Xue, Yingyin Mao, Chunyan Wang, Xing Yao, Bharat B. Biswal   +5 more
wiley   +1 more source

Direct estimation of activity concentration in regional voxels with application to 177Lu peptide receptor radionuclide therapy

Medical Physics, Volume 53, Issue 4, April 2026.
Abstract Background Quantitative SPECT in radionuclide‐therapy is limited by partial‐volume effects (PVEs). The implementation of regional voxels (r.v.), estimating mean activity concentrations in regions directly from projections, offers a promising alternative for the geometry‐specification to reduce PVEs.
Johan Gustafsson, Erik Larsson, Katarina Sjögreen Gleisner   +2 more
wiley   +1 more source

A Cross‐Sectional Survey of Evidence Needs for Medicinal Products in Europe With a Focus on Real‐World Evidence

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 4, April 2026.
ABSTRACT Purpose To assess views among different stakeholders around evidence needs during assessment of clinical effects across the medicinal product life cycle, with a focus on real‐world evidence (RWE) in regulatory and health technology assessor (HTA)/payer decision‐making.
Maria Melinder, Fabian Windfuhr, Tanja Dahlqvist, Carla Torre, Bruno Sepodes, Peter G. M. Mol, Diogo Almeida, Isabella Ekheden, Nils Feltelius, Kit Roes, Sieta T. de Vries, Björn Wettermark   +11 more
wiley   +1 more source

Uptake and Binding of At‐211 Into K‐ and Cs‐Derivatives of Alpha‐Zirconium Phosphate Nanoplatelets for Use as a Targeted Alpha Therapy Delivery Platform

Small Science, Volume 6, Issue 4, April 2026.
Intercalation of At‐211 between the layers of K‐ or Cs‐zirconium phosphate. The ion exchange behavior of K‐ and Cs‐derivatives of α‐zirconium phosphate, A‐ZrP, with the targeted alpha therapy (TAT) radionuclide 211At, as At+ and AtO+, has been investigated. The K‐ZrP shows strong affinity for both At+ and AtO+, ≥99% uptake.
B. D. Imansha Madhushan, Adrianna L. Orsi, Jehan S. Perera, Jennifer M. Pyles, Christine C. Lawrence, Marcus Le, Gabriel C. Tabacaru, Shayden R. Fritz, Lauren A. McIntosh, Sherry J. Yennello, Jonathan D. Burns   +10 more
wiley   +1 more source

Compound Library Screening Identified Cladribine as a Novel Radiosensitizer for Prostate Cancer

Cancer Science, Volume 117, Issue 4, Page 1136-1147, April 2026.
The combination of cladribine and irradiation significantly suppressed the growth of DU145‐derived tumors compared with the DMSO plus irradiation group in the mouse model. In addition, it also elevated the percentage of γH2AX‐positive cells after irradiation.
Toshiki Oka, Koji Hatano, Shohei Katsuki, Tomohiro Kanaki, Shunsuke Inoguchi, Masaru Tani, Akihiro Yoshimura, Yuki Horibe, Yutong Liu, Nesrine Sassi, Yohei Okuda, Akinaru Yamamoto, Toshihiro Uemura, Gaku Yamamichi, Yu Ishizuya, Takuji Hayashi, Yoshiyuki Yamamoto, Taigo Kato, Atsunari Kawashima, Keisuke Tamari, Bangzhong Lin, Akiyoshi Tani, Kazutake Tsujikawa, Yutaka Takahashi, Kazuhiko Ogawa, Shawn E. Lupold, Norio Nonomura   +26 more
wiley   +1 more source

European Society of Neuroendocrine Tumors (ENETS) 2025 guidance paper for lung and thymic carcinoids

Journal of Neuroendocrinology, Volume 38, Issue 4, April 2026.
Abstract This ENETS guidance paper, developed by a multidisciplinary working group, provides up‐to‐date and practical advice on the diagnosis and management of lung and thymic carcinoids, based on recent developments and study results. These recommendations aim to provide practical recommendations for the diagnosis, treatment and follow‐up of these ...
Eric Baudin, Alice Durand, Wieneke Buikhuisen, Jaume Capdevila, Martyn Caplin, Christophe M. Deroose, Clarisse Dromain, Antongiulio Faggiano, Pier Luigi Filosso, Gregory Kaltsas, Marco Volante, Thomas Walter, Rocio Garcia‐Carbonero   +12 more
wiley   +1 more source

Focal Spot, Summer/Fall 2005 [PDF]

, 2005
https://digitalcommons.wustl.edu/focal_spot_archives/1100/thumbnail ...
Dissertações e Teses
core   +1 more source