Results 1 to 10 of about 88,932 (342)

Characterization of Treponema pallidum Dissemination in C57BL/6 Mice

open access: yesFrontiers in Immunology, 2021
The spirochetal pathogen Treponema pallidum causes 5 million new cases of venereal syphilis worldwide each year. One major obstacle to syphilis prevention and treatment is the lack of suitable experimental animal models to study its pathogenesis ...
Simin Lu   +8 more
doaj   +2 more sources

The occurrence of Treponema spp. in gingival plaque from dogs with varying degree of periodontal disease. [PDF]

open access: yesPLoS ONE, 2018
Periodontal disease is common in dogs and is initiated by gingival plaque composed of several hundred bacterial species. Some of these species have specifically been pointed out as potential periodontal pathogens, such as Treponema spp.
Janna Nises   +3 more
doaj   +2 more sources

Diversity of Treponema denticola and Other Oral Treponeme Lineages in Subjects with Periodontitis and Gingivitis

open access: yesMicrobiology Spectrum, 2021
More than 75 species/species-level phylotypes belonging to the genus Treponema inhabit the human oral cavity. Treponema denticola is commonly associated with periodontal disease, but the etiological roles and ecological distributions of other oral ...
Huihui Zeng   +4 more
doaj   +2 more sources

Associations between digital dermatitis lesion grades in dairy cattle and the quantities of four Treponema species

open access: yesVeterinary Research, 2018
Digital dermatitis (DD) presents as painful, ulcerative or proliferative lesions that lead to bovine lameness affecting economic efficiency and animal welfare. Although DD etiological agent(s) have not been established, it is widely accepted that DD is a
Caroline Beninger   +7 more
doaj   +2 more sources

Treponema species enrich the gut microbiota of traditional rural populations but are absent from urban individuals

open access: yesNew Microbes and New Infections, 2019
There is a significant gap in our knowledge of the microbe–host relationship between urban and traditional rural populations. We conducted a large-scale study to examine the gut microbiota of different traditional rural and urban lifestyles in human ...
E. Angelakis   +19 more
doaj   +2 more sources

Detection of Treponema pallidum tpp47 DNA in clinical samples of syphilis patients [PDF]

open access: yesEuropean Journal of Medical Research
Backgrounds To investigate the relationship between the presence of Treponema pallidum DNA in saliva, serum, and cerebrospinal fluid (CSF) in patients with different stages of syphilis.
Yongjun Meng   +5 more
doaj   +2 more sources

Treponema pallidum Protein Tp0136 Induces Spheroidization of Vascular Endothelial Cells, Resulting in Widened Intercellular Junctions and Enhanced Vascular Permeability [PDF]

open access: yesSmall Science
The Treponema pallidum membrane protein Tp0136 facilitates Treponema pallidum dissemination, and the permeability of vasculature is intricately linked to the density of the vascular endothelial barrier, which is strongly associated with the morphology of
Yu Lin   +5 more
doaj   +2 more sources

Treponema denticola in microflora of bovine periodontitis

open access: yesPesquisa Veterinária Brasileira, 2015
Periodontitis in cattle is an infectious purulent progressive disease associated with strict anaerobic subgingival biofilm and is epidemiologically related to soil management at several locations of Brazil. This study aimed to detect Treponema species in
Ana Carolina Borsanelli   +3 more
doaj   +2 more sources

Global phylogeny of Treponema pallidum lineages reveals recent expansion and spread of contemporary syphilis

open access: yesNature Microbiology, 2021
Syphilis, which is caused by the sexually transmitted bacterium Treponema pallidum subsp. pallidum, has an estimated 6.3 million cases worldwide per annum.
M. Beale   +37 more
semanticscholar   +1 more source

A suite of PCR-LwCas13a assays for detection and genotyping of Treponema pallidum in clinical samples

open access: yesNature Communications, 2022
The performance of commonly used assays for diagnosis of syphilis varies considerably depending on stage of infection and sample type. In response to the need for improved syphilis diagnostics, we develop assays that pair PCR pre-amplification of the ...
Wentao Chen   +13 more
semanticscholar   +1 more source

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