Results 101 to 110 of about 7,910 (222)
Oral Phageome as Potential Modulators of Periodontal Dysbiosis. A Systematic Review
ABSTRACT Introduction The oral phageome, comprising bacteriophages inhabiting the oral cavity, has been proposed as a potential modulator of periodontal health and disease. This systematic review synthesizes current evidence on interactions between bacteriophages, key periodontal bacteria, and the host in periodontitis.
Marco Bonilla +3 more
wiley +1 more source
Periodontal disease affects nearly 60% of the global adult population. Its costs to individuals, and to society as a whole, are enormous. As periodontal disease develops, there is a shift in the composition of the oral microbial community.
Juni Sarkar +3 more
semanticscholar +1 more source
ABSTRACT Objective To compare the adjunctive efficacy of a hyaluronic acid (HA) gel with 0.20% chlorhexidine (CHX) during nonsurgical periodontal therapy in periodontal patients over 6 months. Methods A single‐blind, randomized, controlled trial included 40 healthy, nonsmoking adults with periodontitis.
Andrea Scribante +4 more
wiley +1 more source
FlaG homologue has been found in several bacteria including spirochetes; however, its function is poorly characterised. In this report, we investigated the role of TDE1473, a putative FlaG, in the spirochete Treponema denticola, a keystone pathogen of ...
K. Kurniyati +4 more
semanticscholar +1 more source
Characteristics of the Health‐Associated Oral Microbiome in Young Nonhuman Primates
The oral microbiome of healthy younger nonhuman primates, as a preclinical model of the human oral cavity, was evaluated. The results provide seminal details of the oral microbiome in this disease model to elucidate specific microbial changes.
J. L. Ebersole, O. A. Gonzalez
wiley +1 more source
Treponema denticola Induces Epithelial Barrier Dysfunction in Polarized Epithelial Cells.
Treponema denticola, an anaerobic spirochete found mainly in the oral cavity, is associated with periodontal disease and has a variety of virulence factors. Although in vitro studies have shown that T.
Yuichiro Kikuchi +5 more
semanticscholar +1 more source
Treponema denticola is an important periodontal pathogen capable of tissue invasion. Its chymotrypsin-like proteinase (CTLP) can degrade a number of basement membrane components in vitro, thus suggesting a contribution to tissue invasion by the ...
Emilia Marttila +7 more
doaj +1 more source
Killing of Treponema denticola by Mouse Peritoneal Macrophages
Treponema denticola has been identified as an important cause of periodontal disease and hypothesized to be involved in extra-oral infections. The objective of this study was to investigate the role of T. denticola cell length and motility during mouse peritoneal macrophages in vitro uptake. Macrophages, incubated under aerobic and anaerobic conditions,
GAIBANI, PAOLO +7 more
openaire +3 more sources
Treponema denticola synthesizes phosphatidylcholine through a licCA‐dependent CDP‐choline pathway identified only in the genus Treponema. However, the mechanism of conversion of CDP‐choline to phosphatidylcholine remained unclear.
M. Vences-Guzmán +8 more
semanticscholar +1 more source
A novel glycan modifies the flagellar filament proteins of the oral bacterium Treponema denticola
While protein glycosylation has been reported in several spirochetes including the syphilis bacterium Treponema pallidum and Lyme disease pathogen Borrelia burgdorferi, the pertinent glycan structures and their roles remain uncharacterized.
K. Kurniyati +8 more
semanticscholar +1 more source

