Results 101 to 110 of about 7,910 (222)

Oral Phageome as Potential Modulators of Periodontal Dysbiosis. A Systematic Review

open access: yesOral Diseases, EarlyView.
ABSTRACT Introduction The oral phageome, comprising bacteriophages inhabiting the oral cavity, has been proposed as a potential modulator of periodontal health and disease. This systematic review synthesizes current evidence on interactions between bacteriophages, key periodontal bacteria, and the host in periodontitis.
Marco Bonilla   +3 more
wiley   +1 more source

The Treponema denticola PAS Domain-Containing Histidine Kinase Hpk2 Is a Heme Binding Sensor of Oxygen Levels

open access: yesJournal of Bacteriology, 2018
Periodontal disease affects nearly 60% of the global adult population. Its costs to individuals, and to society as a whole, are enormous. As periodontal disease develops, there is a shift in the composition of the oral microbial community.
Juni Sarkar   +3 more
semanticscholar   +1 more source

Efficacy of a Hyaluronic Acid‐Based Gel Versus 0.20% Chlorhexidine in Nonsurgical Periodontal Therapy: A Single‐Blind Randomized Clinical Trial

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective To compare the adjunctive efficacy of a hyaluronic acid (HA) gel with 0.20% chlorhexidine (CHX) during nonsurgical periodontal therapy in periodontal patients over 6 months. Methods A single‐blind, randomized, controlled trial included 40 healthy, nonsmoking adults with periodontitis.
Andrea Scribante   +4 more
wiley   +1 more source

A pleiotropic role of FlaG in regulating the cell morphogenesis and flagellar homeostasis at the cell poles of Treponema denticola

open access: yesCellular Microbiology, 2018
FlaG homologue has been found in several bacteria including spirochetes; however, its function is poorly characterised. In this report, we investigated the role of TDE1473, a putative FlaG, in the spirochete Treponema denticola, a keystone pathogen of ...
K. Kurniyati   +4 more
semanticscholar   +1 more source

Characteristics of the Health‐Associated Oral Microbiome in Young Nonhuman Primates

open access: yesMolecular Oral Microbiology, EarlyView.
The oral microbiome of healthy younger nonhuman primates, as a preclinical model of the human oral cavity, was evaluated. The results provide seminal details of the oral microbiome in this disease model to elucidate specific microbial changes.
J. L. Ebersole, O. A. Gonzalez
wiley   +1 more source

Treponema denticola Induces Epithelial Barrier Dysfunction in Polarized Epithelial Cells.

open access: yesThe Bulletin of Tokyo Dental College, 2018
Treponema denticola, an anaerobic spirochete found mainly in the oral cavity, is associated with periodontal disease and has a variety of virulence factors. Although in vitro studies have shown that T.
Yuichiro Kikuchi   +5 more
semanticscholar   +1 more source

Intracellular localization of Treponema denticola chymotrypsin-like proteinase in chronic periodontitis

open access: yesJournal of Oral Microbiology, 2014
Treponema denticola is an important periodontal pathogen capable of tissue invasion. Its chymotrypsin-like proteinase (CTLP) can degrade a number of basement membrane components in vitro, thus suggesting a contribution to tissue invasion by the ...
Emilia Marttila   +7 more
doaj   +1 more source

Killing of Treponema denticola by Mouse Peritoneal Macrophages

open access: yesJournal of Dental Research, 2010
Treponema denticola has been identified as an important cause of periodontal disease and hypothesized to be involved in extra-oral infections. The objective of this study was to investigate the role of T. denticola cell length and motility during mouse peritoneal macrophages in vitro uptake. Macrophages, incubated under aerobic and anaerobic conditions,
GAIBANI, PAOLO   +7 more
openaire   +3 more sources

1,2-diacylglycerol choline phosphotransferase catalyzes the final step in the unique Treponema denticola phosphatidylcholine biosynthesis pathway

open access: yesMolecular Microbiology, 2017
Treponema denticola synthesizes phosphatidylcholine through a licCA‐dependent CDP‐choline pathway identified only in the genus Treponema. However, the mechanism of conversion of CDP‐choline to phosphatidylcholine remained unclear.
M. Vences-Guzmán   +8 more
semanticscholar   +1 more source

A novel glycan modifies the flagellar filament proteins of the oral bacterium Treponema denticola

open access: yesMolecular Microbiology, 2016
While protein glycosylation has been reported in several spirochetes including the syphilis bacterium Treponema pallidum and Lyme disease pathogen Borrelia burgdorferi, the pertinent glycan structures and their roles remain uncharacterized.
K. Kurniyati   +8 more
semanticscholar   +1 more source

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