Results 81 to 90 of about 7,910 (222)

Treponema denticola chymotrypsin-like protease as associated with HPV-negative oropharyngeal squamous cell carcinoma

British Journal of Cancer, 2018
An opportunistic oral pathogen, Treponema denticola (Td), has been linked to orodigestive carcinogenesis, but its role in oropharyngeal squamous cell carcinoma (OPSCC) has remained open. We evaluated the presence of Td chymotrypsin-like protease (Td-CTLP)
A. K. Kylmä, Lauri Jouhi, Dyah Listyarifah, Hesham Mohamed, A. Mäkitie, S. Remes, C. Haglund, T. Atula, M. Nieminen, T. Sorsa, J. Hagström   +10 more
semanticscholar   +1 more source

Periodontal Status of Type 1 Diabetes Mellitus and Healthy Pregnant Women: A Case–Control Pilot Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Aims This cross‐sectional ‘case–control’ pilot study aimed to compare the size of periodontal wounds, periodontal status and total inflammatory burden between pregnant women with type 1 diabetes mellitus (T1DM) and non‐diabetic pregnant women. Methods Fifteen T1DM pregnant women and 15 healthy pregnant women were included. Clinical parameters (
M. Janc, M. Tomažič, M. Pirc, U. Skalerič, R. Schara   +4 more
wiley   +1 more source

Atypical chemoreceptor arrays accommodate high membrane curvature

Nature Communications, 2020
The main components of the prokaryotic chemotaxis system, chemoreceptors, organize into a hexagonal (P6 symmetry) extended array. Here authors use cryo-ET and report an alternative symmetry (P2) of the chemotaxis apparatus that emerges from a strict ...
Alise R. Muok, Davi R. Ortega, Kurni Kurniyati, Wen Yang, Zachary A. Maschmann, Adam Sidi Mabrouk, Chunhao Li, Brian R. Crane, Ariane Briegel   +8 more
doaj   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Treponema denticola increases MMP-2 expression and activation in the periodontium via reversible DNA and histone modifications

Cellular Microbiology, 2018
Host‐derived matrix metalloproteinases (MMPs) and bacterial proteases mediate destruction of extracellular matrices and supporting alveolar bone in periodontitis.
I. Ateia, P. Sutthiboonyapan, P. Kamarajan, T. Jin, V. Godovikova, Yvonne L. Kapila, J. Fenno   +6 more
semanticscholar   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Treponema denticola: patógeno en procesos periodontales y pulpares

Odontología Sanmarquina, 2012
En la etiología multifactorial de la enfermedad periodontal y procesos pulpares, el factor bacteriano tiene gran relevancia. En estos procesos se identifica una flora polimicrobiana en la que destaca Treponema denticola, una espiroqueta con múltiples ...
Donald Ramos Perfecto, Mario Julio Ávila Campos, Victor Levano Torres   +2 more
doaj   +1 more source

Metagenomic analysis reveals presence of Treponema denticola in a tissue biopsy of the Iceman. [PDF]

PLoS ONE, 2014
Ancient hominoid genome studies can be regarded by definition as metagenomic analyses since they represent a mixture of both hominoid and microbial sequences in an environment.
Frank Maixner, Anton Thomma, Giovanna Cipollini, Stefanie Widder, Thomas Rattei, Albert Zink   +5 more
doaj   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Peri‐Implantitis and Periodontitis: Biological Convergence, Contextual Divergence

Journal of Periodontal Research, EarlyView.
Periodontal and peri‐implant tissues differ and coincide in many aspects, from the clinical and radiological perspective, including histology, microbiology, and molecular markers. Thus, health and disease may also follow different and similar routes.
Pablo Galindo‐Moreno, Pablo Galindo‐Fernandez, Allinson Olaechea, Francisco O'Valle, Abdusalam E. Alrmali, Hom‐Lay Wang, Miguel Padial‐Molina   +6 more
wiley   +1 more source