Functional Characterization of Small Alarmone Synthetase and Small Alarmone Hydrolase Proteins from Treponema denticola. [PDF]
Wang M, Tang NY, Xie S, Watt RM.
europepmc +1 more source
Periodontitis treatment and microbiome in a patient with FAM20A mutation: Case study of 1.5 years
Abstract Background Enamel‐renal‐gingival syndrome (ERGS) is an autosomal recessive disorder caused by mutations in the FAMily with sequence similarity 20A (FAM20A) gene, and is characterized by amelogenesis imperfecta, delayed or failed tooth eruption, and periodontitis.
John Rong Hao Tay +2 more
wiley +1 more source
BACKGROUND & OBJECTIVE: Endodontic infections are polymicrobial in nature and commonly involve anaerobic bacteria such as Treponema denticola, a spirochete also associated with periodontal disease.
Vanishree Shivakumar +5 more
doaj +1 more source
Molecular docking analysis of thiazo inhibitors with the virulent factor cystalysin from Treponema denticola. [PDF]
Andrew S +5 more
europepmc +1 more source
The Silent Link: Exploring the Impact of Periodontal Diseases on Head and Neck Carcinogenesis
ABSTRACT Objectives Oral dysbiosis can accelerate the progression of head and neck squamous cell carcinoma (HNSCC) by fostering a pro‐inflammatory, immunosuppressive, and metabolically altered environment. This narrative review examines the relationships between periodontitis‐associated bacteria and HNSCC, focusing on their impact on oncogenic pathways,
Yashmin Afshar, Nima Rezaei
wiley +1 more source
Molecular docking analysis of Indole based oxadiazoles with the H-binding protein from Treponema denticola. [PDF]
Kumaran P +5 more
europepmc +1 more source
Unraveling Oral Dysbiosis: Microbial Complexity in Common Oral Diseases
The oral microbiome undergoes dynamic establishment from birth, maturing into a resilient ecosystem. Perturbation of this homeostasis—driven by dietary, immunological, and anatomical factors—triggers dysbiosis, which underpins the pathogenesis of major oral diseases, including dental caries, periodontal disease, salivary gland disorders, oral mucosal ...
Zixi Kang +8 more
wiley +1 more source
The oral microbiome in Hispanics remains largely resilient during mild SARS‐CoV‐2 infection, showing minimal diversity changes, while COVID‐19 vaccination induces increased microbial evenness and compositional shifts. These findings highlight limited infection impact but suggest vaccination transiently reshapes oral microbial ecology.
Daniela Vargas‐Robles +8 more
wiley +1 more source
Anti-σ28 Factor FlgM Regulates Flagellin Gene Expression and Flagellar Polarity of Treponema denticola. [PDF]
Kurniyati K +5 more
europepmc +1 more source
Salivary Microvesicle Methylome and Microbiome Profiles in Periodontitis: An Exploratory Study
ABSTRACT Aim Salivary microvesicles (MVs) are nanosized extracellular vesicles from the host and microbiota whose cargo may mirror the biological state of their parent cells. This cross‐sectional study aimed to explore the diagnostic power of host methylome and microbiome profiles of MVs in various periodontal disease states. Materials and Methods This
Pingping Han +5 more
wiley +1 more source

