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Functional characterization of Dentipain of Treponema denticola
Functional characterization of Dentipain of Treponema denticolaopenaire
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Activation of Complement by Treponema denticola
Journal of Dental Research, 1991Oral spirochetes have been shown to be associated with periodontal diseases and are present in increased numbers in lesions of greater severity. In this study, the interaction of Treponema denticola with human complement, a major antibacterial defense system, was examined. For each of two strains of T.
H A, Schenkein, C R, Berry
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Locomotory characteristics of Treponema denticola
Canadian Journal of Microbiology, 1988Locomotion of pathogenic spirochetes has been suggested as a virulence factor in their pathogenesis. Little is known of the locomotory characteristics of oral anaerobic spirochetes. We have determined the optimal conditions for motility of seven strains of Treponema denticola in menstrua of different viscosities. The viscosity for optimum motility for
F, Pietrantonio +3 more
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Major proteins and antigens of Treponema denticola
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2009Treponema denticola is a Gram-negative, motile, asaccharolytic, anaerobic spirochaete which along with Porphyromonas gingivalis and Tannerella forsythia has been shown to form a bacterial consortium called the Red Complex that is strongly associated with the clinical progression of chronic periodontitis. T.
Paul D, Veith +6 more
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Genetic Manipulation of Treponema denticola
Current Protocols in Microbiology, 2006AbstractThe oral anaerobic spirochete, Treponema denticola, has been implicated in the etiology of human periodontal diseases; however, the molecular basis for the virulence of these organisms is still unclear. Potential pathogenic factors expressed by T. denticola have recently begun to be identified through the development of gene transfer approaches
Howard K, Kuramitsu +2 more
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Oxygen metabolism by Treponema denticola
Oral Microbiology and Immunology, 1999Treponema denticola strains ATCC 35405 and ASLM were found to have moderately active oxygen metabolism and consumed some 0.46 μmol O2/h/mg cell protein in anaerobic growth medium or about ten times this amount in aerobic medium. There appeared to be no differences between the two strains in their oxidative metabolism.
C E, Caldwell, R E, Marquis
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A Study of the Acid Phosphatase of Treponema denticola
Zentralblatt für Bakteriologie, 1990This study describes some of the properties of the acid phosphatase of the potential periodontopathogen Treponema denticola. The highest enzyme activity was found in 87 h old cells. Two optimum pHs for enzyme activity were detected, one at pH 4.8 and another at pH 6.2. Divalent cations did not influence the acid phosphatase of T. denticola. The anion F-
C A, Norton Hughes, W W, Yotis
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Adherence of Treponema denticola to Modified Hydroxyapatite
Journal of Dental Research, 1987Small samples of hydroxyapatite (HA) beads were coated with 10 μL of either saliva, serum, human crevicular fluid, or a preparation of lysosomal enzymes from human polymorphonuclear leucocytes (PMN), before being added to suspensions of Treponema denticola. The beads were then observed with the scanning electron microscope. Abundant T.
G, Cimasoni, B C, McBride
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Antigenic and Structural Analysis of Treponema denticola
Microbiology, 1989Polypeptide and Western immunoblot profiles of subcellular fractions of Treponema denticola ATCC 33520 have been determined by SDS-PAGE of Triton X-100-soluble and -insoluble fractions, a lipopolysaccharide-enriched fraction and purified flagella. Major Triton X-100-soluble polypeptides of 72, 68, 54 and 52 kDa were detected.
A, Cockayne +6 more
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Role of Treponema Denticola in Periodontal Diseases
Critical Reviews in Oral Biology & Medicine, 2001Among periodontal anaerobic pathogens, the oral spirochetes, and especially Treponema denticola, have been associated with periodontal diseases such as early-onset periodontitis, necrotizing ulcerative gingivitis, and acute pericoronitis. Basic research as well as clinical evidence suggest that the prevalence of T.
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