The unique histidine kinase, AtcS, regulates motility and pathogenicity of the periodontal pathobiont, Treponema denticola [PDF]
Treponema denticola is an obligate colonizer of the human gingival crevice and, along with other pathobionts, is highly associated with the development of periodontal disease.
Doaa N. Abdallah +6 more
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Advances in Treponema denticola and oral diseases
Treponema denticola is an important pathogenic Treponema pathogen in the human oral cavity. Early studies have found that Treponema denticola is closely related to the occurrence and development of periodontal diseases.
PENG Ruiting, CHENG Lei, PENG Xian
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Purification of Native Dentilisin Complex from Treponema denticola by Preparative Continuous Polyacrylamide Gel Electrophoresis and Functional Analysis by Gelatin Zymography [PDF]
Periodontal disease is characterized by the destruction of the hard and soft tissues comprising the periodontium. This destruction translates to a degradation of the extracellular matrices (ECM), mediated by bacterial proteases, host-derived matrix ...
Pachiyappan Kamarajan +8 more
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The potential role of genus Treponema in carcinogenesis with a focus on oral squamous cell carcinoma: a scoping review of the evidence [PDF]
Background Current concepts suggest that a dysbiotic environment can promote ‘oral carcinomas.’ Microbiome studies on the oral cavity indicate changes in bacterial disposition in this condition.
Pratibha Gopalkrishna +6 more
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Localization and pathogenic role of the cysteine protease dentipain in Treponema denticola [PDF]
Yuichiro Kikuchi +2 more
exaly +2 more sources
Red-complex bacteria: immunological background leading to the development of head and neck cancers [PDF]
Oral microbiome imbalance is involved in the development of head and neck cancers (HNCs). There is a group of oral pathogens, such as Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola, that creates red-complex.
Karolina Kaźmierczak-Siedlecka +9 more
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Glutathione catabolism by Treponema denticola impacts its pathogenic potential [PDF]
Chu L +4 more
exaly +2 more sources
Detection of Periodontal Pathogens from Dental Plaques of Dogs with and without Periodontal Disease
Dental plaque bacteria are one of the main factors responsible for the development of a periodontal disease, which is the most common infectious disease in dogs.
Jana Kačírová +8 more
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Arginine catabolism by Treponema denticola [PDF]
Treponema denticola, an anaerobe commonly present in the human mouth, ferments various amino acids and glucose. Amino acid analyses indicated that substrate amounts of arginine were utilized by T. denticola growing in a complex, serum-containing medium.
R P, Blakemore, E, Canale-Parola
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Effect of fluoride on Treponema denticola [PDF]
The effect of fluoride on the growth of Treponema denticola was studied. Fluoride, at a concentration of 20 micrograms/ml, was found to suppress the growth of all three strains tested. Growth was completely inhibited by 40 micrograms of fluoride per ml.
C A, Hughes, W W, Yotis
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