Results 51 to 60 of about 7,042 (196)

Aging and periodontitis increase brain dissemination of oral bacteria

Journal of Periodontology, EarlyView.
Abstract Background The microbiome is a dynamic system that changes throughout life. Studies have revealed the relationship between periodontal disease and the oral microbiota; however, the impact of periodontal disease on the expression of senescence markers and on the inflammaging of the oral and systemic microbiome remains unclear.
Ozge Unlu, Tsute Chen, Nil Yakar, Zeliha Guney, Bruce Paster, Isabel Carreras, Alpaslan Dedeoglu, Alpdogan Kantarci   +7 more
wiley   +1 more source

Characterization of the Treponema denticola Virulence Factor Dentilisin [PDF]

, 2020
Treponema denticola is a potent periodontal pathogen that forms a red complex with Porphyromonas gingivalis and Tannerella forsythia. It has many virulence factors, yet there are only a few reports detailing these factors. Among them, dentilisin is a well-documented surface protease.
Kikuchi, Y, Ishihara, K
openaire   +3 more sources

Zinc‐stabilized stannous fluoride modulates the periodontal microbiome, reducing Fusobacteria, key Gram‐negative species, and overall inflammation within an experimental gingivitis clinical trial

Journal of Periodontology, EarlyView.
Abstract Background This study aimed to evaluate the effects of a dentifrice containing stannous fluoride stabilized with zinc phosphate on subgingival microbiome composition and clinical inflammation during experimental gingivitis, compared with a sodium fluoride control. Methods This investigation was conducted as a secondary analysis of a randomized,
Kristopher A. Kerns, Allison A. Naumann, Lay Y. Soon, Erik L. Hendrickson, Abdelahhad Barbour, Dandan Chen, Harsh M. Trivedi, Michael Glogauer, Jeffrey S. McLean   +8 more
wiley   +1 more source

Porphyromonas gingivalis and Treponema denticola Mixed Microbial Infection in a Rat Model of Periodontal Disease

Interdisciplinary Perspectives on Infectious Diseases, 2010
Porphyromonas gingivalis and Treponema denticola are periodontal pathogens that express virulence factors associated with the pathogenesis of periodontitis. In this paper we tested the hypothesis that P. gingivalis and T.
Raj K. Verma, Sunethra Rajapakse, Archana Meka, Clayton Hamrick, Sheela Pola, Indraneel Bhattacharyya, Madhu Nair, Shannon M. Wallet, Ikramuddin Aukhil, Lakshmyya Kesavalu   +9 more
doaj   +1 more source

Designing Polymerase Chain Reaction for Molecular Diagnostics of the Primary Bacterial Cause of Periodontitis [PDF]

Journal of Advanced Biomedical Sciences, 2020
Background & Objective: Periodontal disease, which can become a chronic condition, is an inflammatory disease that upsets the soft and hard structures supporting the teeth. The aim of the present study was to design and develop an in-house PCR Method, to
mohammad soleimani, mohammadreza zolfaghari, abbas morovvati   +2 more
doaj  

Periodontal Status of Type 1 Diabetes Mellitus and Healthy Pregnant Women: A Case–Control Pilot Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Aims This cross‐sectional ‘case–control’ pilot study aimed to compare the size of periodontal wounds, periodontal status and total inflammatory burden between pregnant women with type 1 diabetes mellitus (T1DM) and non‐diabetic pregnant women. Methods Fifteen T1DM pregnant women and 15 healthy pregnant women were included. Clinical parameters (
M. Janc, M. Tomažič, M. Pirc, U. Skalerič, R. Schara   +4 more
wiley   +1 more source

Porphyromonas gingivalis Outer Membrane Vesicles Mediate Coaggregation and Piggybacking of Treponema denticola and Lachnoanaerobaculum saburreum

International Journal of Dentistry, 2013
Porphyromonas gingivalis sheds outer membrane vesicles that contain several virulence factors, including adhesins. In this study, we investigated the ability of P.
Daniel Grenier
doaj   +1 more source

Shotgun Metagenomic Analysis Reveals Taxonomic and Functional Transitions in the Salivary Microbiome During Periodontal Disease Progression

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To characterise multi‐kingdom salivary microbiome profiles across clinically defined periodontal states and identify stage‐specific taxonomic and functional alterations using shotgun metagenomic sequencing. Materials and Methods In this cross‐sectional study, 204 adults (mean age 40.3 ± 7.6 years) from the SECRETO study (NCT01934725 ...
Muhammed Manzoor, Jaakko Leskelä, Eija Könönen, Leo Lahti, Jukka Putaala, Pirkko J. Pussinen, Susanna Paju   +6 more
wiley   +1 more source

Alteration of subgingival microbiome in patients with type 2 diabetes induced by diabetes treatment

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Diabetes and periodontal disease, a bacterial infection involving the oral microbiome, have a bidirectional relationship. However, the relationship between poor glycemic control and the oral microbiome remains unclear. The aim of this study was to assess the direct effect of intensive glycemic control on the oral microbiome ...
Moe Inoue, Akito Sakanaka, Naoto Katakami, Hitoshi Nishizawa, Kazuo Omori, Naohiro Taya, Asuka Ishikawa, Shota Mayumi, Hiroki Takeuchi, Atsuo Amano, Toru Takeshita, Eiichiro Fukusaki, Iichiro Shimomura, Masae Kuboniwa   +13 more
wiley   +1 more source

Tip-oriented adherence of Treponema denticola to fibronectin [PDF]

Infection and Immunity, 1990
The adherence of Treponema denticola to ligands on cell surfaces or in basement membranes of periodontal tissues might play an important role in its pathogenicity. A direct microscopic assay was used to examine the binding of T. denticola to fibronectin and other protein substrates adsorbed on plastic cover slips. All strains of T.
J R, Dawson, R P, Ellen
openaire   +2 more sources