Molecular Screening for Digital Dermatitis-Associated Treponemes in Bovine Ischaemic Teat Necrosis Lesions and Milk in Dairy Cattle [PDF]
PathogensBovine ischaemic teat necrosis (ITN) is a disease affecting the skin of the teats of dairy cows with an unknown aetiopathogenesis. Digital dermatitis (DD)-associated treponemes have previously been suggested as a potential aetiological agent in ITN ...
Hayley E. Crosby-Durrani +3 more
doaj +2 more sources
Red Blood Cell Lysis Pretreatment Can Significantly Improve the Yield of Treponema pallidum DNA from Blood [PDF]
Microbiology Spectrum, 2023 PCR can be a supplement to Treponema serological testing. However, its sensitivity is not satisfactory for blood sample testing. The aim of this study was to investigate whether pretreatment with red blood cell (RBC) lysis could enhance the yield of ...
Zi-Han Wei +5 more
doaj +2 more sources
Successful implementation of a risk assessment and mitigation program to control bovine digital dermatitis at the herd-level [PDF]
Scientific ReportsThis nonrandomized clinical intervention study was designed as a prospective, multicenter group comparison to evaluate the efficacy of a risk assessment and mitigation program to control bovine digital dermatitis (BDD). The program was implemented over a
Jim Weber +11 more
doaj +2 more sources
Treponema pallidum induces pro-inflammatory cytokine secretion in macrophages and macrophage-endothelial co-cultures [PDF]
Frontiers in Cellular and Infection MicrobiologySyphilis, caused by the extracellular bacterium Treponema pallidum ssp. pallidum, is a multi-stage and systemic infection that is lifelong in the absence of treatment. Two host cell types that frequently encounter T.
Sean Waugh +4 more
doaj +2 more sources
Metabolic Footprint of Treponema phagedenis and Treponema pedis Reveals Potential Interaction Towards Community Succession and Pathogenesis in Bovine Digital Dermatitis [PDF]
PathogensBovine digital dermatitis (BDD) is a cattle infection causing hoof lesions and lameness, with treponemes as key pathogens. We analyzed the metabolic activity of Treponema phagedenis and Treponema pedis using gas chromatography–mass spectrometry for ...
Hector M. Espiritu +6 more
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Bovine Digital Dermatitis: Treponema spp. on trimming equipment and chutes – effect of washing and disinfection [PDF]
BMC Veterinary ResearchBackground Digital dermatitis (DD) is a contagious bovine foot disease causing reduced animal welfare and negative economic consequences for the farmer. Treponema spp. are the most important causative agents.
Lina Ahlén +6 more
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Proteomic analysis of the Treponema pallidum subsp. pallidum SS14 strain: coverage and comparison with the Nichols strain proteome [PDF]
Frontiers in MicrobiologyIntroductionStrains of the syphilis spirochete, Treponema pallidum ssp. pallidum, group into one of two deep-branching clades: the Nichols clade or the globally dominant Street Strain 14 (SS14) clade. To date, in-depth proteome-wide analyses have focused
Simon Houston +4 more
doaj +2 more sources
The hare syphilis agent is related to, but distinct from, the treponeme causing rabbit syphilis. [PDF]
PLoS ONEThe treponemes infecting lagomorphs include Treponema paraluisleporidarum ecovar Cuniculus (TPeC) and ecovar Lepus (TPeL), infecting rabbits and hares, respectively. In this study, we described the first complete genome sequence of TPeL, isolate V3603-13,
Petra Pospíšilová +12 more
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High prevalence and genetic diversity of Treponema paraluisleporidarum isolates in European lagomorphs [PDF]
Microbiology SpectrumThe bacterium Treponema paraluisleporidarum causes syphilis in lagomorphs. In a set of 1,095 samples from four species—European brown hare, mountain hare, Corsican hare, and European rabbit—we tested for infection and genotyped the strains that infect ...
Sascha Knauf +19 more
doaj +2 more sources
Frontiers in Cellular and Infection Microbiology, 2021 Bovine digital dermatitis (BDD) is a common infectious disease of digital skin in cattle and an important cause of lameness worldwide, with limited treatment options.
Kerry Newbrook +3 more
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