Results 61 to 70 of about 2,492 (156)

Complete genome sequences of two strains of Treponema pallidum subsp. pertenue from Ghana, Africa: Identical genome sequences in samples isolated more than 7 years apart.

PLoS Neglected Tropical Diseases, 2017
BackgroundTreponema pallidum subsp. pertenue (TPE) is the causative agent of yaws, a multi-stage disease, endemic in tropical regions of Africa, Asia, Oceania, and South America.
Michal Strouhal, Lenka Mikalová, Pavla Havlíčková, Paolo Tenti, Darina Čejková, Ivan Rychlík, Sylvia Bruisten, David Šmajs   +7 more
doaj   +1 more source

A novel syphilis Treponema pallidum lipoprotein peptide antigen diagnostic assay using red cell kodecytes in routine blood centre column agglutination testing platforms

Vox Sanguinis, Volume 119, Issue 8, Page 821-826, August 2024.
Abstract Background and Objectives The detection of treponemal antibodies, which are used to make a diagnosis of syphilis, is important both for diagnostic purposes and as a mandatory blood donor test in most countries. We evaluated the feasibility of using Kode Technology to make syphilis peptide red cell kodecytes for use in column agglutination ...
Suvro Sankha Datta, Radhika Nagappan, Durba Biswas, Debapriya Basu, Kaushik Gupta, Pradip Kumar Mondal, Alexander Tuzikov, Nicolai V. Bovin, Stephen M. Henry   +8 more
wiley   +1 more source

Hemagglutination treponemal test for syphilis [PDF]

Journal of Clinical Microbiology, 1983
Sera from 290 hospital patients were tested to compare the sensitivity, specificity, and reproducibility of the hemagglutination treponemal test for syphilis (HATTS) with the fluorescent treponemal antibody absorption test (FTA-ABS). Complete agreement was obtained between the methods when 142 syphilitic sera from patients with various stages of ...
G, Friedly, M V, Zartarian, J C, Wood, C M, Floyd, E M, Peterson, L M, de la Maza   +5 more
openaire   +2 more sources

Succession of the oral microbiome with the increasing severity of periodontitis

VIEW, Volume 5, Issue 2, April 2024.
Changes in the human microbiome in the development of chronic inflammatory diseases are always an interesting scientific topic. This study focuses on the succession of oral microbiome with the increasing severity of periodontitis. The authors have applied multiple new algorithms, such as SourceTracker, site specialist, neutral community model, and ...
Jun Mi, Mengfan Zhi, Wenyan Kang, Qianyu Liang, Di Tang, Ting Wang, Wenjing Song, Tianyong Sun, Meihui Li, Jinlong Shao, Shaohua Ge, Qiang Feng   +11 more
wiley   +1 more source

An Uncommon Manifestation of a Great Imitator: Gummatous Syphilis of the Liver in an HIV‐Positive Patient

Case Reports in Infectious Diseases, Volume 2024, Issue 1, 2024.
Syphilis is a sexually transmitted infection caused by Treponema pallidum. It progresses in phases and undiagnosed disease can cause considerable morbidity. Tertiary syphilis causes the formation of gummas. Liver involvement is rarely described and usually limited to transaminase elevation during primary syphilis. We present a case of tertiary syphilis
Nadia Solomon, Tom Heller, Tommaso Manciulli, Paola Del Giacomo, Katleen de Gaetano Donati, Enrico Brunetti, Francesco Taccari, Piyush Baindara   +7 more
wiley   +1 more source

Identification of positively selected genes in human pathogenic treponemes: Syphilis-, yaws-, and bejel-causing strains differ in sets of genes showing adaptive evolution.

PLoS Neglected Tropical Diseases, 2019
BackgroundPathogenic treponemes related to Treponema pallidum are both human (causing syphilis, yaws, bejel) and animal pathogens (infections of primates, venereal spirochetosis in rabbits). A set of 11 treponemal genome sequences including those of five
Denisa Maděránková, Lenka Mikalová, Michal Strouhal, Šimon Vadják, Ivana Kuklová, Petra Pospíšilová, Lenka Krbková, Pavlína Koščová, Ivo Provazník, David Šmajs   +9 more
doaj   +1 more source

Treponeme Outer Envelope: Chemical Analysis

Experimental Biology and Medicine, 1976
The chemical composition of the outer envelope (OE) of Treponema phagedenis biovar Kazan 5 was investigated. After cultivation in a lipid-defined medium, the OE was removed from the cells with 0.7 mM sodium dodecyl sulfate. The solubilized OE was reaggregated by dialysis against 20 mM MgCl2, washed, lyophilized, and subjected to chemical analysis.
M S, Wachter, R C, Johnson
openaire   +2 more sources

A Metataxonomic Tool to Investigate the Diversity of Treponema

Frontiers in Microbiology, 2019
The genus Treponema contains a number of human and animal pathogenic as well as symbiotic bacteria that are found in vastly different anatomical and environmental habitats. Our understanding of the species range, evolution, and biology of these important
Luisa K. Hallmaier-Wacker, Luisa K. Hallmaier-Wacker, Simone Lüert, Simone Lüert, Sabine Gronow, Cathrin Spröer, Jörg Overmann, Jörg Overmann, Nicky Buller, Rebecca J. Vaughan-Higgins, Sascha Knauf   +10 more
doaj   +1 more source

Genome analysis of Treponema pallidum subsp. pallidum and subsp. pertenue strains: most of the genetic differences are localized in six regions.

PLoS ONE, 2010
The genomes of eight treponemes including T. p. pallidum strains (Nichols, SS14, DAL-1 and Mexico A), T. p. pertenue strains (Samoa D, CDC-2 and Gauthier), and the Fribourg-Blanc isolate, were amplified in 133 overlapping amplicons, and the restriction ...
Lenka Mikalová, Michal Strouhal, Darina Čejková, Marie Zobaníková, Petra Pospíšilová, Steven J Norris, Erica Sodergren, George M Weinstock, David Šmajs   +8 more
doaj   +1 more source

Reanalysis of Chinese Treponema pallidum samples: all Chinese samples cluster with SS14-like group of syphilis-causing treponemes

BMC Research Notes, 2018
Objective Treponema pallidum subsp. pallidum (TPA) is the causative agent of syphilis. Genetic analyses of TPA reference strains and human clinical isolates have revealed two genetically distinct groups of syphilis-causing treponemes, called Nichols-like
Michal Strouhal, Jan Oppelt, Lenka Mikalová, Natasha Arora, Kay Nieselt, Fernando González-Candelas, David Šmajs   +6 more
doaj   +1 more source