Results 71 to 80 of about 2,998 (201)

Whole genome sequence of the Treponema pallidum subsp. endemicum strain Iraq B: A subpopulation of bejel treponemes contains full-length tprF and tprG genes similar to those present in T. p. subsp. pertenue strains.

PLoS ONE, 2020
Treponema pallidum subsp. endemicum (TEN) is the causative agent of endemic syphilis (bejel). Until now, only a single TEN strain, Bosnia A, has been completely sequenced.
Lenka Mikalová, Klára Janečková, Markéta Nováková, Michal Strouhal, Darina Čejková, Kristin N Harper, David Šmajs   +6 more
doaj   +1 more source

Pharmacokinetics and Safety of Intramuscular Injectable Benzathine Penicillin G in Japanese Healthy Participants

The Journal of Clinical Pharmacology, Volume 64, Issue 10, Page 1259-1266, October 2024.
Abstract An intramuscular (IM) suspension of benzathine penicillin G (BPG) has been used as first‐line therapy for the treatment of syphilis worldwide since its approval in the 1950s. However, there are limited reports about the pharmacokinetics of BPG.
Yinhua Li, Akifumi Okayama, Toshiaki Hagi, Chieko Muto, Susan Raber, Masahito Nagashima   +5 more
wiley   +1 more source

Isolation of digital dermatitis treponemes from cattle hock skin lesions [PDF]

, 2016
Background: Bovine hock lesions present a serious welfare and production issue on dairy farms worldwide. Current theories suggest that trauma is an important factor in the formation of hock lesions, although infection may also play a role in increasing ...
S. Ainsworth (17105155), R. W. Blowey (9369487), S. D. Carter (9369484), Simon Clegg (17155645), N. J. Bell (17218690), J. Bell (4764267), N. J. Evans (7729598)   +6 more
core   +2 more sources

Treponemal infections in hares in The Netherlands [PDF]

Journal of Clinical Microbiology, 1994
Treponemal infections in wild European brown hares (Lepus europaeus) from The Netherlands were diagnosed by means of serological tests for human syphilis and histological demonstration of spirochetes by the Bosma-Steiner silver impregnation method in histological sections of skin lesions.
Lumeij, JT, de Koning, J, Bosma, RB, van der Sluis, JJ, Schellekens, JFP   +4 more
openaire   +3 more sources

Characterization of c‐di‐AMP signaling in the periodontal pathobiont, Treponema denticola

Molecular Oral Microbiology, Volume 39, Issue 5, Page 354-367, October 2024.
Abstract Pathobionts associated with periodontitis, such as Treponema denticola, must possess numerous sensory transduction systems to adapt to the highly dynamic subgingival environment. To date, the signaling pathways utilized by T. denticola to rapidly sense and respond to environmental stimuli are mainly unknown.
Aidan D. Moylan, Dhara T. Patel, Claire O'Brien, Edward J. A. Schuler, Annie N. Hinson, Richard T. Marconi, Daniel P. Miller   +6 more
wiley   +1 more source

Complete genome sequences of two strains of Treponema pallidum subsp. pertenue from Ghana, Africa: Identical genome sequences in samples isolated more than 7 years apart.

PLoS Neglected Tropical Diseases, 2017
BackgroundTreponema pallidum subsp. pertenue (TPE) is the causative agent of yaws, a multi-stage disease, endemic in tropical regions of Africa, Asia, Oceania, and South America.
Michal Strouhal, Lenka Mikalová, Pavla Havlíčková, Paolo Tenti, Darina Čejková, Ivan Rychlík, Sylvia Bruisten, David Šmajs   +7 more
doaj   +1 more source

A public database for the new MLST scheme for Treponema pallidum subsp. pallidum: surveillance and epidemiology of the causative agent of syphilis [PDF]

PeerJ, 2019
Treponema pallidum subsp. pallidum is the causative agent of syphilis, a sexually transmitted disease with worldwide prevalence. Several different molecular typing schemes are currently available for this pathogen. To enable population biology studies of
Linda Grillova, Keith Jolley, David Šmajs, Mathieu Picardeau   +3 more
doaj   +2 more sources

The Effects of Amixicile, A Pyruvate Ferredoxin Oxidoreductase Inhibitor, on Oral Treponemes [PDF]

, 2016
Periodontal disease (PD) is a polymicrobial infection characterized by inflammation of the gingiva, alveolar bone resorption, and tooth loss (edentulism). Treponema denticola along with Porphyromonas gingivalis and Tannerella forsythia are among the “Red
Reed, Lucas A
core   +1 more source

A novel syphilis Treponema pallidum lipoprotein peptide antigen diagnostic assay using red cell kodecytes in routine blood centre column agglutination testing platforms

Vox Sanguinis, Volume 119, Issue 8, Page 821-826, August 2024.
Abstract Background and Objectives The detection of treponemal antibodies, which are used to make a diagnosis of syphilis, is important both for diagnostic purposes and as a mandatory blood donor test in most countries. We evaluated the feasibility of using Kode Technology to make syphilis peptide red cell kodecytes for use in column agglutination ...
Suvro Sankha Datta, Radhika Nagappan, Durba Biswas, Debapriya Basu, Kaushik Gupta, Pradip Kumar Mondal, Alexander Tuzikov, Nicolai V. Bovin, Stephen M. Henry   +8 more
wiley   +1 more source

Succession of the oral microbiome with the increasing severity of periodontitis

VIEW, Volume 5, Issue 2, April 2024.
Changes in the human microbiome in the development of chronic inflammatory diseases are always an interesting scientific topic. This study focuses on the succession of oral microbiome with the increasing severity of periodontitis. The authors have applied multiple new algorithms, such as SourceTracker, site specialist, neutral community model, and ...
Jun Mi, Mengfan Zhi, Wenyan Kang, Qianyu Liang, Di Tang, Ting Wang, Wenjing Song, Tianyong Sun, Meihui Li, Jinlong Shao, Shaohua Ge, Qiang Feng   +11 more
wiley   +1 more source