Results 61 to 70 of about 2,690 (175)

A novel syphilis Treponema pallidum lipoprotein peptide antigen diagnostic assay using red cell kodecytes in routine blood centre column agglutination testing platforms

Vox Sanguinis, Volume 119, Issue 8, Page 821-826, August 2024.
Abstract Background and Objectives The detection of treponemal antibodies, which are used to make a diagnosis of syphilis, is important both for diagnostic purposes and as a mandatory blood donor test in most countries. We evaluated the feasibility of using Kode Technology to make syphilis peptide red cell kodecytes for use in column agglutination ...
Suvro Sankha Datta, Radhika Nagappan, Durba Biswas, Debapriya Basu, Kaushik Gupta, Pradip Kumar Mondal, Alexander Tuzikov, Nicolai V. Bovin, Stephen M. Henry   +8 more
wiley   +1 more source

Succession of the oral microbiome with the increasing severity of periodontitis

VIEW, Volume 5, Issue 2, April 2024.
Changes in the human microbiome in the development of chronic inflammatory diseases are always an interesting scientific topic. This study focuses on the succession of oral microbiome with the increasing severity of periodontitis. The authors have applied multiple new algorithms, such as SourceTracker, site specialist, neutral community model, and ...
Jun Mi, Mengfan Zhi, Wenyan Kang, Qianyu Liang, Di Tang, Ting Wang, Wenjing Song, Tianyong Sun, Meihui Li, Jinlong Shao, Shaohua Ge, Qiang Feng   +11 more
wiley   +1 more source

Membrane Filtration of the Reiter Treponeme [PDF]

Applied Microbiology, 1970
A membrane filtration technique with commercially available membrane filters (Millipore Corp.) was effective for the removal of Reiter treponemes from liquids such as fluorescent-antibody conjugates, to which the organisms are added for adsorption.
F W, Chandler, J W, Clark
openaire   +2 more sources

An Uncommon Manifestation of a Great Imitator: Gummatous Syphilis of the Liver in an HIV‐Positive Patient

Case Reports in Infectious Diseases, Volume 2024, Issue 1, 2024.
Syphilis is a sexually transmitted infection caused by Treponema pallidum. It progresses in phases and undiagnosed disease can cause considerable morbidity. Tertiary syphilis causes the formation of gummas. Liver involvement is rarely described and usually limited to transaminase elevation during primary syphilis. We present a case of tertiary syphilis
Nadia Solomon, Tom Heller, Tommaso Manciulli, Paola Del Giacomo, Katleen de Gaetano Donati, Enrico Brunetti, Francesco Taccari, Piyush Baindara   +7 more
wiley   +1 more source

Beyond appearance: An unusual manifestation of isolated oral secondary syphilis

International Journal of Immunopathology and Pharmacology, 2019
Syphilis is a sexually acquired chronic infection caused by Treponema pallidum and is characterized by a variety of clinical manifestations. The secondary stage of the disease results from the hematogenous and lymphatic dissemination of treponemes after ...
Elena Mari, Maurizio Nudo, Enzo Palese, Luisa Cotticelli, Ciro Cotticelli, Grazia Zino, Rosa Coppola, Federica Maria Di Lella, Gabriele Arcari, Donatella Maria Rodio, Carla Prezioso, Valeria Pietropaolo, Valeria Devirgiliis, Vincenzo Panasiti   +13 more
doaj   +1 more source

Diagnostic capabilities of non-treponemal and treponemal reactions in the early forms of syphilis.

Medicni perspektivi (Medical perspectives), 2017
A comparative analysis of the sensitivity and specificity of immunoblotting against other non-treponemal and treponemal reactions was carried out in 215 patients with early forms of syphilis. A high diagnostic efficiency of immunoblotting in patients with early latent syphilis was established.
openaire   +5 more sources

Identification of positively selected genes in human pathogenic treponemes: Syphilis-, yaws-, and bejel-causing strains differ in sets of genes showing adaptive evolution.

PLoS Neglected Tropical Diseases, 2019
BackgroundPathogenic treponemes related to Treponema pallidum are both human (causing syphilis, yaws, bejel) and animal pathogens (infections of primates, venereal spirochetosis in rabbits). A set of 11 treponemal genome sequences including those of five
Denisa Maděránková, Lenka Mikalová, Michal Strouhal, Šimon Vadják, Ivana Kuklová, Petra Pospíšilová, Lenka Krbková, Pavlína Koščová, Ivo Provazník, David Šmajs   +9 more
doaj   +1 more source

A Metataxonomic Tool to Investigate the Diversity of Treponema

Frontiers in Microbiology, 2019
The genus Treponema contains a number of human and animal pathogenic as well as symbiotic bacteria that are found in vastly different anatomical and environmental habitats. Our understanding of the species range, evolution, and biology of these important
Luisa K. Hallmaier-Wacker, Luisa K. Hallmaier-Wacker, Simone Lüert, Simone Lüert, Sabine Gronow, Cathrin Spröer, Jörg Overmann, Jörg Overmann, Nicky Buller, Rebecca J. Vaughan-Higgins, Sascha Knauf   +10 more
doaj   +1 more source

A Fluorescent Test for Treponemal Antibodies

Experimental Biology and Medicine, 1957
Summary1. A technic for the use of fluorescein labeled antiglobulin as an indicator of treponemal antibody is described. 2. The effect of rotation as an intensifier of fluorescent antibody reactions is determined. 3. Results obtained with fluorescent antibody tests on syphilitic rabbits are compared with results of other treponemal and nontreponemal ...
W E, DEACON, V H, FALCONE, A, HARRIS
openaire   +2 more sources

Genome analysis of Treponema pallidum subsp. pallidum and subsp. pertenue strains: most of the genetic differences are localized in six regions.

PLoS ONE, 2010
The genomes of eight treponemes including T. p. pallidum strains (Nichols, SS14, DAL-1 and Mexico A), T. p. pertenue strains (Samoa D, CDC-2 and Gauthier), and the Fribourg-Blanc isolate, were amplified in 133 overlapping amplicons, and the restriction ...
Lenka Mikalová, Michal Strouhal, Darina Čejková, Marie Zobaníková, Petra Pospíšilová, Steven J Norris, Erica Sodergren, George M Weinstock, David Šmajs   +8 more
doaj   +1 more source