Efficacy and Safety of Generic Fluocinolone Acetonide, Hydroquinone, and Tretinoin Cream Compared With TRI-LUMA for the Treatment of Moderate-To-Severe Melasma in Chinese Patients: A Randomized, Single-Center, Placebo-Controlled Trial. [PDF]
ABSTRACT Background Treatment with fluocinolone acetonide, hydroquinone, and tretinoin cream is the gold standard for melasma; however, the effects of this treatment in the Chinese population remain unclear. Due to the differences between Chinese and Caucasian subjects, further clinical trials in Chinese patients with melasma are needed.
Hu H+7 more
europepmc +2 more sources
Tretinoin peel: a critical view [PDF]
The tretinoin peel, also known as retinoic acid peel, is a superficial peeling often performed in dermatological clinics in Brazil. The first study on this was published in 2001, by Cuce et al., as a treatment option for melasma.
Bagatin, Edileia+2 more
core +11 more sources
One Acne™: A holistic management approach to improve overall skin quality and treatment outcomes in acne with or without sensitive skin. [PDF]
Abstract Acne and sensitive skin can take a profound toll on patients' well‐being, which can be exacerbated if the conditions are experienced together. This narrative review aims to identify appropriate treatments to facilitate a holistic management approach to acne (One Acne™), sensitive skin, and acne‐induced sequelae and describe the role of ...
Kircik L+8 more
europepmc +2 more sources
Tretinoin-based formulations - influence of concentration and vehicles on skin penetration [PDF]
Tretinoin is used in the management of acne and it is part of a gold standard treatment for photoaging. It has also been reported as an agent for superficial chemical peeling in highly concentrated formulations with few considerations about skin ...
BAGATIN E+33 more
core +5 more sources
Comparison of the Modulated Effects of Tretinoin and Calcitriol Treated Mesenchymal Stem Cell Supernatant on Macrophage Functions [PDF]
Background: According to a number of studies, calcitriol and tretinoin are able to regulate differentiation as well as the growth and of mesenchymal stem cells (MSCs).
Esmaeili Gouvarchin Ghaleh, Hadi+2 more
core +2 more sources
Novel tretinoin 0.05% lotion for the once-daily treatment of moderate-to-severe acne vulgaris in a preadolescent population. [PDF]
BackgroundAcne vulgaris (acne) is a common skin condition in children and adolescents. Efficacy of tretinoin is well documented in studies that included pediatric patients (12-18 years of age). With acne routinely presenting in younger patients, data are
Bhatt, Varsha+4 more
core +1 more source
The formation of tretinoin-PEG 6000 solid-solid solution to increase the dissolution rate of tretinoin [PDF]
The formation of solid-solid dispersion of tretinoin which is insoluble in water into water soluble carrier PEG, might accelerate solubility and dissolution rate.
Chairul+3 more
core +3 more sources
Topical Tretinoin Increases the Tropoelastin and Fibronectin Content of Photoaged Hairless Mouse Skin [PDF]
Topical tretinoin treatment of photoaged hairless mice has been shown in previous studies to stimulate formation of a subepidermal zone of new connective tissue characterized by enhanced collagen synthesis.
Kligman, Lorraine H., Schwartz, Elaine
core +1 more source
Muir-Torre syndrome - Treatment with isotretinoin and interferon alpha-2a can prevent tumour development [PDF]
Muir-Torre syndrome is a genodermatosis in which multiple internal malignancies are associated with cutaneous sebaceous tumours and kerato-acanthomas. A 57-year-old man presented with multiple sebaceous tumours, kerato-acanthomas, verrucous carcinoma of ...
Burgdorf, Walter H. C.+3 more
core +1 more source
Concurrent application of tretinoin (retinoic acid) partially protects against corticosteroid-induced epidermal atrophy [PDF]
Cutaneous atrophy arising from prolonged use of potent topical corticosteroids has long been a concern. Thus, it would be advantageous to find an agent which protects against atrophy produced by corticosteroids but at the same time does not impair their ...
Finkel, L. J.+6 more
core +1 more source