Results 131 to 140 of about 13,053 (160)
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Tretinoin (Retinoic Acid) Revisited
New England Journal of Medicine, 1993Although it is easy to dismiss problems such as postinflammatory hyperpigmentation under the rubric of “cosmetic concerns,” pigmentary disorders are a frequent cause of distress because of our soci...
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Archives of Dermatology, 1980
To the Editor.— The recent review of Dr Frank's textbook (Archives116:234,1980) raised several questions about the stability of topical tretinoin in clinical use. The incompatibility of tretinoin with benzoyl peroxide or sunlight might be deduced from the following: marketed tretinoin products contain butylated hydroxytoluene, an antioxidant, to ...
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To the Editor.— The recent review of Dr Frank's textbook (Archives116:234,1980) raised several questions about the stability of topical tretinoin in clinical use. The incompatibility of tretinoin with benzoyl peroxide or sunlight might be deduced from the following: marketed tretinoin products contain butylated hydroxytoluene, an antioxidant, to ...
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Topical tretinoin for photoaged skin
Journal of the American Academy of Dermatology, 1986Daily topical application of 0.05% tretinoin in a cream base was compared with its vehicle with regard to moderation of photoaging changes of the face and forearms. In comparison with the control tissue, tretinoin-treated tissue examined by light and electron microscopy showed the following effects: replacement of the atrophic epidermis by hyperplasia,
James J. Leyden +3 more
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Archives of Dermatology, 1974
To the Editor.— The filamentous form of the yeast-like organism that incites tinea versicolor can be eliminated by a variety of topically applied medicaments. These either possess antifungal activity or are "keratolytic" chemicals that enhance desquamation and make the horny layer unfavorable for fungus growth.
Otto H. Mills, Albert M. Kligman
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To the Editor.— The filamentous form of the yeast-like organism that incites tinea versicolor can be eliminated by a variety of topically applied medicaments. These either possess antifungal activity or are "keratolytic" chemicals that enhance desquamation and make the horny layer unfavorable for fungus growth.
Otto H. Mills, Albert M. Kligman
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Tretinoin Therapy for Monilethrix
Archives of Dermatology, 1974To the Editor.— Monilethrix is a dysplasia of the hair shaft; it is characterized by eliptical nodes separated by constricted internodes at which the medulla is lacking. The disease is uncommon; its mechanism of production is unknown; and up until the present, to our knowledge, no effective treatment had been known.
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Treatment of Photoaged Skin with Topical Tretinoin
Skin Pharmacology and Physiology, 1993Once-daily application of tretinoin to photodamaged facial skin for 0-12 months results in substantial clinical and histologic improvement. As regards appearance, fine wrinkles become effaced, dyspigmentations fade, surface becomes smooth and develops a ‘rosy glow’.
Albert M. Kligman, James J. Leyden
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Topical tretinoin in acne therapy
Journal of the American Academy of Dermatology, 1998Topical tretinoin has been a mainstay of acne therapy for nearly 25 years. It is available in a number of formulations and concentrations, including 0.025%, 0.05% and 0.1% cream, 0.1% and 0.25% gel, and 0.1% liquid solution. A new formulation, incorporating 0.1% in a microsphere gel formulation, has recently become available.
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2020
Topical retinoic acid (RA) has been used as a routine in dermatological practice for over one century. It is an excellent option to treat many cosmetic affections and abnormalities, thanks to its capacity to promote controlled desquamation of the epidermis, as shown by the studied literature.
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Topical retinoic acid (RA) has been used as a routine in dermatological practice for over one century. It is an excellent option to treat many cosmetic affections and abnormalities, thanks to its capacity to promote controlled desquamation of the epidermis, as shown by the studied literature.
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Tretinoin and Photocarcinogenicity: An Update
Journal of Toxicology: Cutaneous and Ocular Toxicology, 1993AbstractConflicting reports have described topical tretinoin as either enhancing or inhibiting ultraviolet radiation-induced tumorigenesis in albino hairless mice. A number of reviews have addressed the issue, with two assessing the relevance of the hairless mouse model.
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Tretinoin and Antibiotic Therapy in Acne Vulgaris*
Southern Medical Journal, 1974The intent of this report is to summarize our experience in treating acne with tretinoin, antibiotics, and the combination of both agents. For patients with predominantly comedonal acne or in those with inflammatory acne who for one reason or another cannot receive antibiotics, tretinoin alone is used.
Albert M. Kligman +3 more
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