Results 81 to 90 of about 16,131 (224)

Basal cell carcinomas without histological confirmation and their treatment : an audit in four European regions [PDF]

open access: yes, 2012
Summary- Background: Limited data are available on how often basal cell carcinomas (BCCs) are clinically diagnosed without histological confirmation and how they are treated. Objectives Within the framework of the EPIDERM project, an audit was conducted
Ahti, T.   +9 more
core   +1 more source

Gene expression regulation by retinoic acid

open access: yesJournal of Lipid Research, 2002
Over the last quarter century, more than 532 genes have been put forward as regulatory targets of retinoic acid. In some cases this control is direct, driven by a liganded heterodimer of retinoid receptors bound to a DNA response element; in others, it ...
James E. Balmer, Rune Blomhoff
doaj   +1 more source

Role of topical tretinoin in melanoma and dysplastic nevi. [PDF]

open access: yes, 1986
The retinoids have been investigated extensively as chemopreventive and therapeutic agents in a variety of neoplasms. They have been shown to inhibit the proliferation of transformed cell lines in vitro and transplanted tumors in vivo. In cultured murine
Edwards, L, Levine, NS, Meyskens, FL
core  

A Pilot Trial of Pioglitazone HCl and Tretinoin in ALS: Cerebrospinal Fluid Biomarkers to Monitor Drug Efficacy and Predict Rate of Disease Progression

open access: yesNeurology Research International, 2012
Objectives. To determine if therapy with pioglitazone HCl and tretinoin could slow disease progression in patients with ALS. Levels of tau and pNFH in the cerebrospinal fluid were measured to see if they could serve as prognostic indicators. Methods.
Todd D. Levine   +6 more
doaj   +1 more source

Targeted Topical Delivery of Retinoids in the Management of Acne Vulgaris: Current Formulations and Novel Delivery Systems

open access: yesPharmaceutics, 2019
Acne vulgaris is a common inflammatory pilosebaceous condition that affects 80−90% of adolescents. Since the introduction of tretinoin over 40 years ago, topical retinoid products have been a mainstay of acne treatment.
Gemma Latter   +4 more
doaj   +1 more source

The Use of Tranexamic Acid to Treat Melasma: A Systematic Review and Meta‐Analysis

open access: yesDermatologic Therapy, Volume 2026, Issue 1, 2026.
Introduction Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine that inhibits bleeding due to its effects on plasminogen conversion, approved by the FDA to treat menorrhagia and prevent bleeding in hemophilia patients undergoing dental extraction.
Nabila Scabine Pessotti   +7 more
wiley   +1 more source

Finasteride Side Effects and Post-Finasteride Syndrome in Male Androgenic Alopecia [PDF]

open access: yes, 2015
Finasteride is in present a relatively frequent prescribed drug for male androgenic alopecia. The adverse effects reported by some patients seem to be notable, consisting of various (physical, mental/ neurological, sexual, etc.) manifestations which are ...
Ioana, Paunica   +3 more
core   +3 more sources

Efficacy of Eflornithine Hydrochloride Cream in the Treatment of Melasma: A Randomized, Double‐Blinded, Split‐Face–Controlled Pilot Trial

open access: yesDermatologic Therapy, Volume 2026, Issue 1, 2026.
Background Melasma treatment remains challenging with variable response to conventional lightening agents. Polyamine inhibition via ornithine decarboxylase 1 (ODC1) may offer an alternative approach, with eflornithine hydrochloride being an established ODC1 inhibitor. Objectives To compare the efficacy and safety of eflornithine hydrochloride 13% cream
Jonathan Yongwei Boey   +7 more
wiley   +1 more source

Nuclear Receptors as Therapeutic Targets for Neurodegenerative Diseases: Lost in Translation [PDF]

open access: yes, 2019
Neurodegenerative diseases are characterized by a progressive loss of neurons that leads to a broad range of disabilities, including severe cognitive decline and motor impairment, for which there are no effective therapies.
Codocedo, Juan F.   +3 more
core   +1 more source

A Double Blind Immunohistological Study Of The Effect Of Topical Tretinoin On Photoaged Skin

open access: yesIndian Journal of Dermatology, 1998
Fifteen very fair women with mild to moderate photoaging in there 60’s were tested by doubled blind immunohistological study. Tretinoin 0.05% cream applied daily was compared to its vehicle with regards to epidermal, basal, spinous
Bose Sumit Kumar
doaj  

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