Results 81 to 90 of about 15,648 (249)

A randomized trial assessing the effectiveness of different concentrations of isotretinoin in the management of lichen planus [PDF]

open access: yes, 2006
The aim of our 10-year study was to test the effectiveness of topical therapy based on 0. 18% isotretinoin, comparing it with that most frequently used, i.e. at 0.05% concentration.
CARINI, Francesco   +3 more
core   +1 more source

Alcohol Dehydrogenase 4‐Mediated Retinol Metabolism Inhibits Hepatocellular Carcinoma Progression Through Inhibiting the Wnt/β‐Catenin Pathway

open access: yesMedComm – Oncology, Volume 4, Issue 2, June 2025.
The downregulation of ADH4 expression induces hepatocyte apoptosis, thereby contributing to liver fibrosis and the initiation of hepatocellular carcinoma (HCC). Moreover, sustained suppression of ADH4 in HCC cells disrupts retinoic acid synthesis, leading to reduced expression of the Wnt/β‐catenin signaling inhibitor WIF‐1 via RARs/RXRs‐mediated ...
Jiaying Li   +10 more
wiley   +1 more source

Comparison of efficacy and tolerability of tretinoin gel 0.05% with adapalene gel 0.1% in treating mild to moderate acne vulgaris

open access: yesFiyz̤, 2018
Background: Acne vulgaris is an inflammatory skin disease. Topical retinoids with significant anti-inflammatory properties are used for treatment of acne. The common side effect of topical retinoids is local irritation.
Akram Ansar   +4 more
doaj  

Does treatment of acne with Retin A and tetracycline cause adverse effects? [PDF]

open access: yes, 2004
Self-Adverse reactions to long-term tetracycline therapy are rare, and most will occur within 2 months of initiating therapy (strength of recommendation [SOR]: B, systematic review of ecological studies).
Burroughs, Martha, Kelly, Barbara F.
core  

From Monotherapy to Adjunctive Therapies: Application of Dermocosmetics in Acne Management Across Australia and New Zealand

open access: yesAustralasian Journal of Dermatology, Volume 66, Issue 4, Page 189-198, June 2025.
ABSTRACT Acne vulgaris is a globally prevalent dermatological disease, with its severity ranging from mild to severe. While moderate to severe acne often requires topical or systemic pharmaceutical therapy, mild to moderate acne may be managed with dermocosmetics, which are over‐the‐counter skincare agents with active ingredients that target acne ...
Ryan De Cruz   +7 more
wiley   +1 more source

Comparison between 1% Tretinoin Peeling Versus 70% Glycolic Acid Peeling in the Treatment of Female Patients with Melasma

open access: yesمجله دانشکده پزشکی اصفهان, 2012
Background: Melasma is an irregular brownish pigmentation that appears on the face of young to middle-aged women, especially of Asian races, which may contribute to various emotional disturbances.
Gita Faghihi   +2 more
doaj  

Alopecia Areata: Pathogenesis, Diagnosis, and Therapies

open access: yesMedComm, Volume 6, Issue 5, May 2025.
This review probed into the immune factors in the pathogenesis of AA, focusing on the small molecule drugs and biologics for the treatment of AA, and anticipated the research direction in terms of the pathogenesis and targeted therapy of AA. It aims to emphasize the necessity for further exploration of its immunological pathogenesis and therapeutic ...
Tianyou Ma   +7 more
wiley   +1 more source

A comparative study of topical 5% tranexamic acid and triple combination therapy for the treatment of melasma in Indian population

open access: yesPigment International, 2019
Introduction Melasma is an acquired hyperpigmentary disorder and poses great therapeutic challenge and has a high recurrence rate. Topical 5% tranexamic acid (TA) is a novel and safe alternative therapy for melasma.
Sandeep Khuraiya   +4 more
doaj   +1 more source

Hedgehog signaling pathway and its targets for treatment in basal cell carcinoma [PDF]

open access: yes, 2012
Basal cell carcinoma (BCC) of the skin is the most common type of cancer, and accounts for up to 40% of all cancers in the United States with a growing incidence rate in the last decades in all developed countries.
CUCCHI, DANILO   +3 more
core   +3 more sources

Prevention of Post‐Inflammatory Hyperpigmentation in Skin of Colour: A Systematic Review

open access: yesAustralasian Journal of Dermatology, Volume 66, Issue 3, Page 119-126, May 2025.
ABSTRACT Background/Objectives Post‐inflammatory hyperpigmentation (PIH) impacts all skin tones with a heightened predilection for Fitzpatrick skin types (FST) III‐VI. Preventative measures include pre‐ and post‐intervention approaches, such as sunscreen and corticosteroids. This systematic review aims to summarise the preventative measure outcomes for
Kristie Mar   +5 more
wiley   +1 more source

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