We demonstrate that variation in environmental inputs in early ontogeny can, in part, account for divergence in brain development and cognitive performance in brown trout. We also unveil a partial compensatory mechanism to address nutrient deprivation through bioconversion and routing of crucial omega‐3 fatty acids to brain membranes.
J. Peter Koene+4 more
wiley +1 more source
Granulysin Antimicrobial Activity Promotes Dormancy in Mycobacterium tuberculosis
Exploiting a high‐dimensional mass cytometry approach, we demonstrate that CD56+ lymphocytes promote Mycobacterium tuberculosis dormancy by delivering granulysin, a cytotoxic effector molecule with known antimicrobial activity. ABSTRACT Human tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) remains a global public health threat.
Sarah Schmidiger+17 more
wiley +1 more source
Continuous Exposure of Nonobese Adult Male Rats to a Soft-Textured, Readily Absorbable Diet Induces Insulin Resistance and Derangements in Hepatic Glucose and Lipid Metabolism. [PDF]
Yamaguchi F+5 more
europepmc +1 more source
Biocompatible and biodegradable liposomes were developed to encapsulate naringenin (N) and berberine (B), enhancing their stability and bioavailability. Their effects on thermogenesis and browning in 3T3‐L1 preadipocyte cells compared to their free forms were investigated.
Elif Didem Örs Demet+7 more
wiley +1 more source
Associations between diet quality scores and cardiometabolic status in young Japanese women: A cross-sectional study. [PDF]
Oono F+6 more
europepmc +1 more source
Fractionation of Edible Fats: Model Fat‐Oil Separation in Decanter Centrifuge
A model system was investigated, and fat crystal agglomerates were effectively separated from oil using a lab‐scale decanter centrifuge. High hydrostatic pressure on the bowl wall results in a compacted cake. Low cake axial transport velocity allows sufficient time for the olein to be removed from the cake pores.
Myrofora Kyrimlidou+4 more
wiley +1 more source
Ultrastructural characterization of white adipocytes in a mouse model with enhanced sequestration of fatty acids in adipose tissue. [PDF]
Zhang Y, Tomoo K, Lai YH, Henderson GC.
europepmc +1 more source
The study showed that vitamin C treatment was better than gallic acid, and its combination with gallic acid enhanced the therapeutic effect of gallic acid. Vitamin C and the combination of gallic acid and vitamin C produced better histological changes in the retina of the diabetic rats than gallic acid alone, while the combined therapy produced better ...
He Wang+4 more
wiley +1 more source
Evaluation of FXR Activity in Pollutants Identified in Sewage Sludge and Subsequent <i>in Vitro</i> and <i>in Vivo</i> Characterization of Metabolic Effects of Triphenyl Phosphate. [PDF]
Yang Y+7 more
europepmc +1 more source
What's new? Too often, children treated for B‐cell acute lymphocytic leukemia (B‐ALL) experience relapse. Here, the authors investigate the role of dyslipidemia in leukemia progression. Higher adipogenicity in bone marrow mesenchymal stem cells, and increased triglyceride accumulation, are associated with higher risk of death.
Lili Song+10 more
wiley +1 more source