Results 281 to 290 of about 9,492,801 (363)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

The PROTECT trial: Effect of titrated versus conventional induction of general anaesthesia using a target-controlled infusion system on haemodynamics in patients undergoing non-cardiac surgery - protocol for a multicentre, expertise-based randomised controlled trial. [PDF]

BMJ Open
Funk S, Lohri MD, Kopp Lugli A, Schindler C, Wiencierz A, Mnich K, Schläpfer M, Gaberdiel AP, Puhan MA, Steiner LA, Gomes NV, Dell-Kuster S.   +11 more
europepmc   +1 more source

Breathing control training as a treatment for functional seizures (BREATHS trial): a multicentre, assessor-blinded, randomised controlled efficacy and acceptability trial study protocol. [PDF]

BMJ Open
Kanaan R, Duncan R, Mihalopoulos C, Braat S, O'Brien TJ, Velakoulis D, Kwan P, Mulder RT, Cook M, Mullen S, Mayne D, Oliver G, Eleftheriadis D, Ameen O, Chatterton ML, D'Souza W, Nicolo JP, Perucca P, Winton-Brown T, Zaloumis S, Berlowitz D.   +20 more
europepmc   +1 more source

A phase 2 study of orally administered live biotherapeutic salmonella-IL2 with FOLFIRINOX for stage IV pancreatic cancer. [PDF]

Cancer Immunol Immunother
Batist G, Kavan P, Augustin L, Schottel J, Moradian J, Lee JT, Saltzman D.   +6 more
europepmc   +1 more source