Results 301 to 310 of about 9,492,801 (363)
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Der Ophthalmologe, 2021
This article presents some high-quality and/or frequently cited glaucoma studies. The LiGHT study, which compared selective laser trabeculoplasty (SLT) with eye drops for reducing intraocular pressure (IOP) in ocular hypertension or early primary open-angle glaucoma (POAG), a British study on real-world results after SLT treatment and the ZAP study ...
Nikolaus, Hommer, Anton, Hommer
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This article presents some high-quality and/or frequently cited glaucoma studies. The LiGHT study, which compared selective laser trabeculoplasty (SLT) with eye drops for reducing intraocular pressure (IOP) in ocular hypertension or early primary open-angle glaucoma (POAG), a British study on real-world results after SLT treatment and the ZAP study ...
Nikolaus, Hommer, Anton, Hommer
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Archives of Surgery, 1984
The ability of a small-scale random-control clinical trial comprising less than 500 patients to disclose clinically important differences between treatment groups depends on the event rate in the control group. The high rate of wound infection after abdominal operations has attracted many trials of methods of antibiotic prophylaxis.
M, Evans, A V, Pollock
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The ability of a small-scale random-control clinical trial comprising less than 500 patients to disclose clinically important differences between treatment groups depends on the event rate in the control group. The high rate of wound infection after abdominal operations has attracted many trials of methods of antibiotic prophylaxis.
M, Evans, A V, Pollock
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Pharmaceutisch Weekblad Scientific Edition, 1983
Randomized controlled clinical trials are being exposed to severe criticism in recent years. It is questioned if the use of placebos in such trials is ethically justified. This and other ethical problems will be discussed in this paper. Ethical problems include, besides the use of placebos, obtainment of informed consent and the belief in 'treatment ...
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Randomized controlled clinical trials are being exposed to severe criticism in recent years. It is questioned if the use of placebos in such trials is ethically justified. This and other ethical problems will be discussed in this paper. Ethical problems include, besides the use of placebos, obtainment of informed consent and the belief in 'treatment ...
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Archives of Neurology, 1989
Controlled clinical trials are becoming increasingly frequent in neurology. A review of the literature indicates that several trials have serious flaws in study design and conduct that render the results questionable or uninterpretable. These reports, together with my own experience with the trial of plasmapheresis in the treatment of acute Guillain ...
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Controlled clinical trials are becoming increasingly frequent in neurology. A review of the literature indicates that several trials have serious flaws in study design and conduct that render the results questionable or uninterpretable. These reports, together with my own experience with the trial of plasmapheresis in the treatment of acute Guillain ...
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Explanatory trials versus pragmatic trials
BMJ, 2014Researchers assessed the effectiveness of weekly delivery of low dose high frequency therapeutic ultrasound in conjunction with standard care for hard to heal venous leg ulcers. A multicentre pragmatic two arm randomised controlled trial study design was used.
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New Scientist, 2011
Osagie K. Obasogie's criticism of clinical trials contains a number of misleading assumptions, including the implication that a clinical trial is by definition a drug trial (22 January, p 24).
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Osagie K. Obasogie's criticism of clinical trials contains a number of misleading assumptions, including the implication that a clinical trial is by definition a drug trial (22 January, p 24).
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Frontiers in Bioscience, 2006
A clinical trial is a research study in human patients aimed at answering specific health questions. If a clinical trial is well-conducted, it is the fastest way to find treatments that work in people and ways to improve health. A clinical trial is one of the final stages of a long research process.
GIACINTI L., LOPEZ M., GIORDANO A.
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A clinical trial is a research study in human patients aimed at answering specific health questions. If a clinical trial is well-conducted, it is the fastest way to find treatments that work in people and ways to improve health. A clinical trial is one of the final stages of a long research process.
GIACINTI L., LOPEZ M., GIORDANO A.
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Molecular Biotechnology, 2001
This article reviews some of the issues involved in evaluating vaccines in humans. Vaccine trials are required for licensure and are essential for demonstrating a vaccine's safety and protective efficacy. The formal framework of phase I, II, and III trials is described, with particular emphasis on the choice of hypotheses, trial design, and biases that
C P, Farrington, E, Miller
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This article reviews some of the issues involved in evaluating vaccines in humans. Vaccine trials are required for licensure and are essential for demonstrating a vaccine's safety and protective efficacy. The formal framework of phase I, II, and III trials is described, with particular emphasis on the choice of hypotheses, trial design, and biases that
C P, Farrington, E, Miller
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The Journal of Rheumatology
Mrs. Ellis (a pseudonym) is a 57-year-old woman with a 10-year history of rheumatoid arthritis (RA) and a previous episode of transverse myelitis with residual pain and weakness.After the patient's insufficient response to methotrexate (MTX) and upon realizing that tumor necrosis factor inhibitors are relatively contraindicated in demyelinating disease,
Victor S. Sloan +2 more
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Mrs. Ellis (a pseudonym) is a 57-year-old woman with a 10-year history of rheumatoid arthritis (RA) and a previous episode of transverse myelitis with residual pain and weakness.After the patient's insufficient response to methotrexate (MTX) and upon realizing that tumor necrosis factor inhibitors are relatively contraindicated in demyelinating disease,
Victor S. Sloan +2 more
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Nursing Management, 2005
Are you involved in inviting patients to join clinical trials? The National electronic Library for Health (NeLH) has developed a website for people who are asked to take part, writes Ruth Williams.
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Are you involved in inviting patients to join clinical trials? The National electronic Library for Health (NeLH) has developed a website for people who are asked to take part, writes Ruth Williams.
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