Results 51 to 60 of about 13,219,076 (270)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A variational method to study the Zakharov equation

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2005
A variational method given by Ritz has been applied to the Zakharov equation to construct an analytical solution. The solution of Zakharov equation gives a good description of both linear and nonlinear evolutions of instabilities generated in waves due ...
Arun Kumar
doaj   +1 more source

The traveling wave mode for nonlinear Biswas–Milovic equation in magneto-optical wave guide coupling system with Kudryashov’s law of refractive index

open access: yesResults in Physics, 2021
This paper studies the traveling wave modes for nonlinear Biswas–Milovic equation in magneto-optical wave guide coupling system with Kudryashov’s law of refractive index.
Li-Feng Guo, Wan-Rong Xu
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Meshless Solution of Incompressible Flow Over Backward-Facing Step

open access: yesCivil and Environmental Engineering, 2016
Article presents the use of the meshless method for numerical simulation of incompressible fluid flow. The article presents the implementation of the meshless local Petrov-Galerkin method (MLPG), with Navier-Stokes equation formulated using the local ...
Mužík Juraj
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Development and refinement of the Variational Method based on Polynomial Solutions of Schrödinger Equation

open access: yesOpen Engineering, 2020
The variational method is known as a powerful and preferred technique to find both analytical and numerical solutions for numerous forms of anharmonic oscillator potentials.
Maiz Fethi
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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