Results 11 to 20 of about 506,753 (297)

Trial Sequential Analysis in systematic reviews with meta-analysis [PDF]

BMC Medical Research Methodology, 2017
Background Most meta-analyses in systematic reviews, including Cochrane ones, do not have sufficient statistical power to detect or refute even large intervention effects. This is why a meta-analysis ought to be regarded as an interim analysis on its way
Jørn Wetterslev, Janus Christian Jakobsen, Christian Gluud   +2 more
doaj   +3 more sources

Trial sequential analysis: plain and simple [PDF]

Korean Journal of Anesthesiology, 2021
Alessandro De Cassai, Laura Pasin, Annalisa Boscolo, Michele Salvagno, Paolo Navalesi   +4 more
doaj   +4 more sources

Trial sequential analysis: Quality improvement for meta-analysis

Indian Journal of Anaesthesia
Indubala Maurya, Ayush Lohiya, Ashish Solanki   +2 more
doaj   +3 more sources

Understanding the trial sequential analysis graph in meta-analysis

Saudi Journal of Anaesthesia
Abhijit Nair, Nitin K Borkar
doaj   +3 more sources

Stroke treatment academic industry roundtable recommendations for individual data pooling analyses in stroke [PDF]

, 2016
Pooled analysis of individual patient data from stroke trials can deliver more precise estimates of treatment effect, enhance power to examine prespecified subgroups, and facilitate exploration of treatment-modifying influences.
Khatri, Pooja, Lees, Kennedy R., STAIR IX Collaborators,   +2 more
core   +1 more source

Exploring the Benefits of Adaptive Sequential Designs in Time-to-Event Endpoint Settings [PDF]

, 2010
Sequential analysis is frequently employed to address ethical and financial issues in clinical trials. Sequential analysis may be performed using standard group sequential designs, or, more recently, with adaptive designs that use estimates of treatment ...
Emerson, Sarah C, Emerson, Scott S., Rudser, Kyle   +2 more
core   +2 more sources

A Meta- and Trial Sequential Analysis [PDF]

, 2015
Objectives Periodontal treatment might reduce adverse pregnancy outcomes. The efficacy of periodontal treatment to prevent preterm birth, low birth weight, and perinatal mortality was evaluated using meta-analysis and trial sequential analysis.
Allareddy, Veerasathpurush, Gluud, Christian, Karimbux, Nadeem, Schwendicke, Falk   +3 more
core   +1 more source

Exercise for lower limb osteoarthritis : systematic review incorporating trial sequential analysis and network meta-analysis [PDF]

, 2013
Objective: To determine whether there is sufficient evidence to conclude that exercise interventions are more effective than no exercise control and to compare the effectiveness of different exercise interventions in relieving pain and improving function
Dziedzic, Krysia S., Foster, Nadine E., Healey, Emma L., Jordan, Joanne L., Peat, George M., Uthman, Olalekan A., van der Windt, Danielle A.   +6 more
core   +4 more sources

Stochastic models of evidence accumulation in changing environments [PDF]

, 2015
Organisms and ecological groups accumulate evidence to make decisions. Classic experiments and theoretical studies have explored this process when the correct choice is fixed during each trial. However, we live in a constantly changing world. What effect
Josic, Kresimir, Kilpatrick, Zachary P., Veliz-Cuba, Alan   +2 more
core   +3 more sources

Quantitative assessment of lncRNA H19 polymorphisms and cancer risk: a meta-analysis based on 48,166 subjects

Artificial Cells, Nanomedicine, and Biotechnology, 2020
Recently, numerous studies have been performed to detect the association between H19 polymorphisms and cancer susceptibility. However, their results were inconsistent and controversial.
Xu Liu, Yating Zhao, Ying Li, Jian Zhang
doaj   +1 more source