Results 41 to 50 of about 509,115 (295)

Relationship Between the ApaI (rs7975232), BsmI (rs1544410), FokI (rs2228570), and TaqI (rs731236) Variants in the Vitamin D Receptor Gene and Urolithiasis Susceptibility: An Updated Meta-Analysis and Trial Sequential Analysis

Frontiers in Genetics, 2020
The relationship between urolithiasis and vitamin D receptor (VDR) gene variants is still under debate according to the available published literature. To assess correlations between VDR gene variants ApaI (rs7975232), BsmI (rs1544410), FokI (rs2228570),
Guangyuan Chen, Cong Hu, Yuxuan Song, Mengxi Xiu, Wanfeng Liang, Ningjing Ou, Xiaoqiang Liu, Peng Huang, Peng Huang   +8 more
doaj   +1 more source

The effect and safety of Tai Chi on bone health in postmenopausal women: A meta-analysis and trial sequential analysis

Frontiers in Aging Neuroscience, 2022
BackgroundTai Chi may be a promising exercise to prevent and control bone loss in postmenopausal women. This meta-analysis and trial sequential analysis aimed to evaluate the effect and safety of Tai Chi on bone health in postmenopausal women.MethodSeven
Xiaobo Liu, Chengzhi Jiang, Rong Fan, Tianyu Liu, Yuxi Li, Dongling Zhong, Luxiang Zhou, Tao Liu, Juan Li, Rongjiang Jin, Rongjiang Jin   +10 more
doaj   +1 more source

Adding epoetin alfa to intense dose-dense adjuvant chemotherapy for breast cancer : randomized clinical trial [PDF]

, 2013
BACKGROUND: The AGO-ETC trial compared 5-year relapse-free survival of intense dose-dense (IDD) sequential chemotherapy with epirubicin (E), paclitaxel (T), and cyclophosphamide (C) (IDD-ETC) every 2 weeks vs conventional scheduled epirubicin ...
Bois, Andreas du, Hinke, Axel, Huober, Jens, Jackisch, Christian, Kreienberg, Rolf, Kuhn, Walther, Kurbacher, Christian, Lueck, Hans-Joachim, Moebus, Volker, Nitz, Ulrike, Runnebaum, Ingo B., Schneeweiss, Andreas, Thomssen, Christoph, Untch, Michael   +13 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Safety and Efficacy of Roxadustat for Anemia in Patients With Chronic Kidney Disease: A Meta-Analysis and Trial Sequential Analysis

Frontiers in Medicine, 2021
Background: Roxadustat, a hypoxia-inducible factor prolyl-hydroxylase inhibitor (HIF-PHI), has been used to treat anemia in patients with chronic kidney disease (CKD).
Chao Liu, Zhangning Fu, Jiawei Jiang, Kun Chi, Xiaodong Geng, Zhi Mao, Chengcheng Song, Guannan Sun, Quan Hong, Guangyan Cai, Xiangmei Chen, Xuefeng Sun   +11 more
doaj   +1 more source

Sequential Effects in Judgements of Attractiveness: The Influences of Face Race and Sex [PDF]

, 2013
In perceptual decision-making, a person’s response on a given trial is influenced by their response on the immediately preceding trial. This sequential effect was initially demonstrated in psychophysical tasks, but has now been found in more complex ...
A Kondo, A Kondo, A Mantonakis, AJ O’Toole, Alex L. Jones, CA Meissner, D Gentner, DB Wright, DB Wright, Dinkar Sharma, DJ Kelly, DT Levin, DT Levin, G Rhodes, Ian D. Stephen, JB Freeman, JM Miller, K Hugenberg, KD Cassidy, KL Johnson, L Damisch, L Page, M Glanzer, MA Gernsbacher, MA Zárate, MA Zárate, MJ Bernstein, MK Holland, PC Quinn, PM Walker, R Reber, Robin S. S. Kramer, SJ Stroessner, T Mussweiler, T Mussweiler, T Valentine, TA Ito, TA Ito, W Bruine de Bruin, W Jesteadt, WJ Matthews, Y Attali   +41 more
core   +3 more sources

Major mistakes or errors in the use of trial sequential analysis in systematic reviews or meta-analyses – the METSA systematic review

BMC Medical Research Methodology
Background Systematic reviews and data synthesis of randomised clinical trials play a crucial role in clinical practice, research, and health policy. Trial sequential analysis can be used in systematic reviews to control type I and type II errors, but ...
Christian Gunge Riberholt, Markus Harboe Olsen, Joachim Birch Milan, Sigurlaug Hanna Hafliðadóttir, Jeppe Houmann Svanholm, Elisabeth Buck Pedersen, Charles Chin Han Lew, Mark Aninakwah Asante, Johanne Pereira Ribeiro, Vibeke Wagner, Buddheera W. M. B. Kumburegama, Zheng-Yii Lee, Julie Perrine Schaug, Christina Madsen, Christian Gluud   +14 more
doaj   +1 more source

The Effect of Magnesium Intake on Stroke Incidence: A Systematic Review and Meta-Analysis With Trial Sequential Analysis

Frontiers in Neurology, 2019
Background: The effect of magnesium on stroke has been consistently discussed less, and the results of previous studies have been contradictory. We reviewed the latest literature and quantified robust evidence of the association between magnesium intake ...
Binghao Zhao, Binghao Zhao, Lei Hu, Yifei Dong, Jingsong Xu, Yiping Wei, Dongliang Yu, Jianjun Xu, Wenxiong Zhang   +8 more
doaj   +1 more source

Dissociating Explicit and Implicit Timing in Parkinson\u2019s Disease Patients: Evidence from Bisection and Foreperiod Tasks [PDF]

, 2018
A consistent body of literature reported that Parkinson\u2019s disease (PD) is marked by severe deficits in temporal processing. However, the exact nature of timing problems in PD patients is still elusive.
Capizzi, Mariagrazia, Correa, \uc1ngel, Di Giacopo, Raffaella, Mioni, Giovanna, Stablum, Franca, Vallesi, Antonino   +5 more
core   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source