Results 61 to 70 of about 509,115 (295)

Efficacy and Safety of Daprodustat Vs rhEPO for Anemia in Patients With Chronic Kidney Disease: A Meta-Analysis and Trial Sequential Analysis

Frontiers in Pharmacology, 2022
Introduction: Daprodustat, a novel hypoxia-inducible factor prolyl-hydroxylase inhibitor (HIF-PHI), its efficacy and safety remain unclear. Thus, we conducted this meta-analysis aiming at investigating its efficacy and safety on the treatment of patients
Zhangning Fu, Zhangning Fu, Xiaodong Geng, Xiaodong Geng, Kun Chi, Kun Chi, Chengcheng Song, Chengcheng Song, Di Wu, Chao Liu, Chao Liu, Quan Hong, Quan Hong   +12 more
doaj   +1 more source

Sequential tests and estimates after overrunning based on $p$-value combination

, 2008
Often in sequential trials additional data become available after a stopping boundary has been reached. A method of incorporating such information from overrunning is developed, based on the ``adding weighted Zs'' method of combining $p$-values.
Ding, Keyue, Hall, W. J.
core   +1 more source

Sequence effects in the categorization of tones varying in frequency [PDF]

, 2004
In contrast to exemplar and decision-bound categorization models, the memory and contrast models described here do not assume that long-term representations of stimulus magnitudes are available.
Abeles, Baird, Gordon D. A. Brown, Helson, Holland, Hu, Kiang, Laming, Laming, Lockhead, Luce, Luce, Luce, Marley, Mori, Mori, Morris, Neil Stewart, Nosofsky, Petzold, Petzold, Schifferstein, Stewart, Ward, Ward, Ward, Ward, Weber   +27 more
core   +1 more source

A Pocock approach to sequential meta‐analysis of clinical trials [PDF]

Research Synthesis Methods, 2013
Three recent papers have provided sequential methods for meta‐analysis of two‐treatment randomized clinical trials. This paper provides an alternate approach that has three desirable features. First, when carried out prospectively (i.e., we only have the results up to the time of our current analysis), we do not require knowledge of the information ...
Jonathan J, Shuster, Josef, Neu
openaire   +2 more sources

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim, Natalie Bradford, David Brain, Sameera Senanayake, Sanjeewa Kularatna, Kate Young, Christine Cashion, Tim Hassall, Susanna Cramb   +8 more
wiley   +1 more source

Lack of reproducibility of trial sequential analyses: a meta-epidemiological study

Trials
Systematic reviews and meta-analyses are essential tools for synthesizing evidence from multiple studies. Recently, trial sequential analyses (TSAs) have gained popularity as a component of meta-analyses, helping researchers dynamically monitor evidence ...
Xing Xing, Yining Wang, Yipeng Wang, Mohammad Hassan Murad, Lifeng Lin   +4 more
doaj   +1 more source

Cerebral Embolic Protection Devices in Transcatheter Aortic Valve Implantation: Meta‐Analysis With Trial Sequential Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background We aimed to reevaluate randomized controlled trial data on outcomes of cerebral embolic protection device use during transcatheter aortic valve implantation.
Nav Warraich, Michel Pompeu Sá, Xander Jacquemyn, Toshiki Kuno, Derek Serna‐Gallegos, Ibrahim Sultan   +5 more
doaj   +1 more source

Optimal stopping times for estimating Bernoulli parameters with applications to active imaging [PDF]

, 2018
We address the problem of estimating the parameter of a Bernoulli process. This arises in many applications, including photon-efficient active imaging where each illumination period is regarded as a single Bernoulli trial. We introduce a framework within
Goyal, Vivek K., Medin, Safa C., Murray-Bruce, John   +2 more
core   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

The clinical efficacy of intravenous IgM-enriched immunoglobulin (pentaglobin) in sepsis or septic shock: a meta-analysis with trial sequential analysis

Annals of Intensive Care, 2019
Background Sepsis is characterized by a complex immune response. This meta-analysis evaluated the clinical effectiveness of intravenous IgM-enriched immunoglobulin (IVIgGM) in patients with sepsis and septic shock.
Jie Cui, Xuxia Wei, Haijin Lv, Yuntao Li, Ping Li, Zhen Chen, Genglong Liu   +6 more
doaj   +1 more source