Trial Sequential Analysis in systematic reviews with meta-analysis [PDF]
Background Most meta-analyses in systematic reviews, including Cochrane ones, do not have sufficient statistical power to detect or refute even large intervention effects. This is why a meta-analysis ought to be regarded as an interim analysis on its way
Jørn Wetterslev +2 more
doaj +3 more sources
Trial sequential analysis: plain and simple [PDF]
Alessandro De Cassai +4 more
doaj +4 more sources
Trial sequential analysis: Quality improvement for meta-analysis
Indubala Maurya +2 more
doaj +3 more sources
Understanding the trial sequential analysis graph in meta-analysis
Abhijit Nair, Nitin K Borkar
doaj +3 more sources
Bromocriptine in peripartum cardiomyopathy: A meta-analysis with trial sequential analysis. [PDF]
Abstract Bromocriptine has been proposed as a disease-modifying therapy for peripartum cardiomyopathy (PPCM). The long-term outcomes of bromocriptine use remain uncertain. We conducted a systematic review, meta-analysis and trial sequential analysis (TSA) to assess the long-term efficacy and safety of bromocriptine in combination with
Adamu UG +3 more
europepmc +3 more sources
A Meta- and Trial Sequential Analysis [PDF]
Objectives Periodontal treatment might reduce adverse pregnancy outcomes. The efficacy of periodontal treatment to prevent preterm birth, low birth weight, and perinatal mortality was evaluated using meta-analysis and trial sequential analysis.
Allareddy, Veerasathpurush +3 more
core +1 more source
Parallel Simulations for Analysing Portfolios of Catastrophic Event Risk [PDF]
At the heart of the analytical pipeline of a modern quantitative insurance/reinsurance company is a stochastic simulation technique for portfolio risk analysis and pricing process referred to as Aggregate Analysis.
Bahl, Aman +3 more
core +2 more sources
Stochastic models of evidence accumulation in changing environments [PDF]
Organisms and ecological groups accumulate evidence to make decisions. Classic experiments and theoretical studies have explored this process when the correct choice is fixed during each trial. However, we live in a constantly changing world. What effect
Josic, Kresimir +2 more
core +3 more sources
Stroke treatment academic industry roundtable recommendations for individual data pooling analyses in stroke [PDF]
Pooled analysis of individual patient data from stroke trials can deliver more precise estimates of treatment effect, enhance power to examine prespecified subgroups, and facilitate exploration of treatment-modifying influences.
Khatri, Pooja +2 more
core +1 more source
The preservation of quartz grain surface textures following vehicle fire and their use in forensic enquiry [PDF]
During a terrorist trial, dispute arose as to whether the temperature produced in a car fire was sufficient to destroy quartz grain surface textures.
Bull, PA +5 more
core +1 more source

